Results 141 to 150 of about 388,905 (379)
Advanced Science, EarlyView.The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang +12 more
wiley +1 more source
Context Driven Label Fusion for segmentation of Subcutaneous and Visceral Fat in CT Volumes [PDF]
arXiv, 2015 Quantification of adipose tissue (fat) from computed tomography (CT) scans is conducted mostly through manual or semi-automated image segmentation algorithms with limited efficacy. In this work, we propose a completely unsupervised and automatic method to identify adipose tissue, and then separate Subcutaneous Adipose Tissue (SAT) from Visceral Adipose
arxiv
The metabolic origins of big size in aquatic mammals [PDF]
arXiv, 2022 The group of large aquatic mammals has representatives being the largest living beings on earth, surpassing the weight and size of dinosaurs. In this paper, we present some empirical evidence and a mathematical model to argue that fat accumulation in marine mammals triggers a series of metabolic events that result in these animals' increased size.
arxiv
The urea cycle of rat white adipose tissue
RSC Advances, 2015 White adipose tissue urea-cycle enzymes showed a high activity and gene expression, second only to liver in catalytic capacity.
Sofía Arriarán +4 more
openaire +4 more sources
Advanced Science, EarlyView.Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu +13 more
wiley +1 more source
Automatic Segmentation of Muscle Tissue and Inter-muscular Fat in Thigh and Calf MRI Images [PDF]
, 2019 Magnetic resonance imaging (MRI) of thigh and calf muscles is one of the most effective techniques for estimating fat infiltration into muscular dystrophies. The infiltration of adipose tissue into the diseased muscle region varies in its severity across, and within, patients.
arxiv +1 more source
A potential model for hepatic regulation of peripheral adipose tissue expansion [PDF]
, 2023 Given the established relationship between liver and white adipose tissue, we hypothesize that hepatokines—particularly adropin—are the source of coordinated gene expression in peripheral adipose tissue driving fat mass expansion.https ...
Anuciado, Rea +2 more
core +1 more source
Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism
Advanced Science, EarlyView.Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley +1 more source
Lactobacillus paracasei N1115 attenuates obesity in high‐fat diet‐induced obese mice
Food Science &Nutrition, Volume 11, Issue 1, Page 418-427, January 2023., 2023 Lactobacillus paracasei N1115 relieved high fat diet induced obesity. Lactobacillus paracasei N1115 decreased body weight, fat accumulation and hyperlipidemia by increasing the abundance of beneficial bacteria (Allobaculum and L. Zeae) and decreased harmful bacteria (Turicibacter).
Yanan Sun +3 more
wiley +1 more source
A single-cell atlas of human and mouse white adipose tissue
Nature, 2021 Margo P. Emont +37 more
semanticscholar +1 more source