Results 71 to 80 of about 1,749 (260)

Choice, Chance and Control

open access: yesVoices in Bioethics, 2018
This essay was runner-up in the Voices in Bioethics 2017 Essay Contest in Prompt 1: Thought Experiment. Dana Horowitz is currently an undergraduate at Tufts University.
Dana Horowitz
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

The Line that Divides us:

open access: yesRevista Brasileira de Estudos da Presença
A common factor among white people is the denial that they are racialized subjects, so that they use white fragility and innocence as strategies to protect and enjoy privilege and racial superiority. By the other hand, decolonial art is made up of a set
Amanda Cunha
doaj  

Black Innocence and the White Jury

open access: yesMichigan Law Review, 1985
Racial prejudice has come under increasingly close scrutiny during the past thirty years, yet its influence on the decisionmaking of criminal juries remains largely hidden from judicial and critical examination. In this Article, Professor Johnson takes a close look at this neglected area.
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Symbolism of the color white in jane Austen’s works

open access: yesTạp chí Khoa học và Công nghệ
The color white's symbolic meaning in Jane Austen's writings reflects a complex portrayal that goes beyond simple beauty. Austen purposefully uses white to represent innocence, purity, and social norms, especially when it comes to how women are portrayed
Huỳnh Ngọc Mai Kha   +1 more
doaj  

'The wedding of Kraljević Marko' on the day of White shrove in Štrpce [PDF]

open access: yesBaština, 2018
The paper discusses 'The Wedding of Kraljević Marko', the event of a collective character, named after a famous epic character in Serbian tradition, which is practised in Štrpce on the day of White Shrove.
Pavlović Aleksandar S.
doaj  

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