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White matter hyperintensities and chronicity of depression
Journal of Psychiatric Research, 2005White matter hyperintensities (WMHs) on T(2)-weighted magnetic resonance imaging (MRI) of the brain are associated with advanced age and late-life depression. Most investigations predominantly found these lesions in frontal lobe and basal ganglia supporting the hypothesis of a fronto-striatal dysfunction in depression.
Angela, Heiden +11 more
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White Matter Hyperintensities and Imaging Patterns of Brain Ageing in the General Population.
Brain, 2016 White matter hyperintensities are associated with increased risk of dementia and cognitive decline. The current study investigates the relationship between white matter hyperintensities burden and patterns of brain atrophy associated with brain ageing ...
Güray Erus, Georg Homuth, Henry Völzke
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Neuropathologic correlates of white matter hyperintensities
Neurology, 2008White matter hyperintensities (WMH) are commonly seen on neuroimaging scans, but their underlying histopathologic substrate is unclear. The aim of this work was to establish the pathologic correlates of WMH in unselected elderly cases using two study designs.
Vanessa G, Young +2 more
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Neurology, 2021
The management of white matter hyperintensities (WMH) of presumed vascular origin is a common challenge in neurologic clinical practice. Such lesions may be identified incidentally during workup for common neurologic complaints such as headaches. In addition, they may be observed on imaging performed as part of stroke assessment and management or as ...
Nawaf, Yassi, Bruce C V, Campbell
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The management of white matter hyperintensities (WMH) of presumed vascular origin is a common challenge in neurologic clinical practice. Such lesions may be identified incidentally during workup for common neurologic complaints such as headaches. In addition, they may be observed on imaging performed as part of stroke assessment and management or as ...
Nawaf, Yassi, Bruce C V, Campbell
openaire +2 more sources
Impact of white matter hyperintensities on surrounding white matter tracts
Neuroradiology, 2018It is unclear how white matter hyperintensities disrupt surrounding white matter tracts. The aim of this tractography study was to determine the spatial relationship between diffusion characteristics along white matter tracts and the distance from white matter hyperintensities.Diffusion tensor 3-T MRI scans were acquired in 29 participants with white ...
William Reginold +5 more
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ISMRM Annual Meeting, 2023
White matter hyperintensities (WMH) have been shown to progress over time but they might regress too. Little is known about the regression of WMH as the main focus has been on progression. We investigate WMH regression and their dynamic properties using diffusion MRI.
Angela Jochems +18 more
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White matter hyperintensities (WMH) have been shown to progress over time but they might regress too. Little is known about the regression of WMH as the main focus has been on progression. We investigate WMH regression and their dynamic properties using diffusion MRI.
Angela Jochems +18 more
openaire +1 more source
White matter volumes and periventricular white matter hyperintensities in aging and dementia
Neurology, 2000To determine the relationship between MRI periventricular white matter hyperintensities, cerebral white matter volumes, neuropathologic findings, and cognitive status in aged individuals.The significance of periventricular white matter hyperintensities seen on MR images in aged individuals remains controversial.
C D, Smith +3 more
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White Matter Hyperintensities in Parkinson's Disease
Archives of Neurology, 1995To verify recent preliminary data indicating that white matter hyperintensities on magnetic resonance imaging are more abundant in patients with Parkinson's disease (PD) than in healthy subjects and to examine possible correlation between these abnormalities and clinical features of PD.Magnetic resonance imaging data on patients with PD and normal ...
Piccini P +7 more
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White Matter Hyperintensities and Cognition
2005Despite the well-established relationship between cerebrovascular disease (CVD) and cognitive decline, confusion remains regarding the clinical importance of the white matter hyperintensities (WMH), also called leukoaraiosis (1), that frequently appear on neuroimaging.
David J. Moser +2 more
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Abdominal fatness and cerebral white matter hyperintensity
Journal of the Neurological Sciences, 2019Although obesity has been proven as a risk factor of metabolic and cardiovascular diseases, there have been few studies addressing the association between obesity and cerebral white matter hyperintensity (WMH) volume with controversial findings.
Ki-Woong Nam +8 more
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