Results 131 to 140 of about 197,800 (388)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Muscle mass decline, arterial stiffness, white matter hyperintensity, and cognitive impairment: Japan Shimanami Health Promoting Program study

Journal of Cachexia, Sarcopenia and Muscle, 2017
There is a close association between frailty and cognitive impairment. However, the underlying contribution of sarcopenia to the development of cognitive impairment is unclear.
K. Kohara, Yoko Okada, Masayuki Ochi, M. Ohara, T. Nagai, Y. Tabara, M. Igase   +6 more
semanticscholar   +1 more source

Resolution of generalized tonic seizures following focal ablative or resective surgery

Epileptic Disorders, EarlyView.
Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman, Itay Tokatly Latzer, Aaron E. L. Warren, Jurriaan M. Peters   +3 more
wiley   +1 more source

Patterns of progressive atrophy vary with age in Alzheimer's disease patients [PDF]

, 2018
Age is not only the greatest risk factor for Alzheimer's disease (AD) but also a key modifier of disease presentation and progression. Here, we investigate how longitudinal atrophy patterns vary with age in mild cognitive impairment (MCI) and AD.
Alzheimer's Disease Neuroimaging Initiative, ., Barnes, J, Biessels, GJ, Cardoso, MJ, Carmichael, OT, Cash, DM, Fiford, CM, Malone, IB, Manning, EN, Modat, M, Nicholas, J, Ourselin, S, Ridgway, GR   +12 more
core  

Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL [PDF]

, 2014
Background and Purpose—White matter hyperintensities (WMH) on MRI are a quantitative marker for sporadic cerebral small vessel disease and are highly heritable.
Adib-Samii, P., Bevan, S., Boon, E. M. J., Bracoud, L., Chabriat, H., De Stefano, N., Dichgans, M., Dotti, M. T., Duering, M., Federico, A., Gonik, M., Herve, D., Jouvent, E., Lesnik Oberstein, S., Liem, M., Malik, R., Markus, H. S., Meitinger, T., Muller-Myhsok, B., Opherk, C., Pachai, C., Pantoni, L., Pescini, F., Pianese, L., Ragno, M., Rosand, J., Rost, N., Silvestri, S., Tournier-Lasserve, E.   +28 more
core   +1 more source

Subjective memory complaints, white matter hyperintensities, and cognitive decline in a population‐based cohort study [PDF]

, 2023
Anisa Dhana, Charles DeCarli, Klodian Dhana, Kristin R. Krueger, Pankaja Desai, Denis A. Evans, Kumar B. Rajan   +6 more
openalex   +1 more source

Bullseye's representation of cerebral white matter hyperintensities

Journal of Neuroradiology, 2018
Visual rating scales have limited capacities to depict the regional distribution of cerebral white matter hyperintensities (WMH). We present a regional-zonal volumetric analysis alongside a visualization tool to compare and deconstruct visual rating scales.3D T1-weighted, T2-weighted spin-echo and FLAIR images were acquired on a 3T system, from 82 ...
Sudre, C. H., Gomez Anson, B., Davagnanam, I., Schmitt, A., Mendelson, A. F., Prados, F., Smith, L., Atkinson, D., Hughes, A. D., Chaturvedi, N., Cardoso, M. J., Barkhof, F., Jaeger, H. R., Ourselin, S.   +13 more
openaire   +6 more sources

Altered neurostructural development in magnetic resonance imaging‐negative pediatric epilepsy: A large‐scale multicenter study of 1919 children

Epilepsia, EarlyView.
Abstract Objective Addressing the poorly understood impact of pediatric epilepsy on neurodevelopment, this large‐scale study delineates age‐ and sex‐stratified neurostructural trajectories in magnetic resonance imaging (MRI)‐negative pediatric epilepsy to identify periods of maximal developmental divergence from healthy controls.
Yingfan Wang, Minghao Li, Huijun Li, Wei Yu, Peilin Jiang, Xinyi Zhou, Ke Hu, Feng Yang, Jiu Chen, Ming Yang, Xiaoshan Wang   +10 more
wiley   +1 more source

Disease activity and cognition in rheumatoid arthritis : an open label pilot study [PDF]

, 2012
Acknowledgements This work was supported in part by NIHR Newcastle Biomedical Research Centre. Funding for this study was provided by Abbott Laboratories.
Birchall, Daniel, Blamire, Andrew M, He, Jiabao, Isaacs, John D, Newton, Julia L, Pearce, Ruth, Raftery, Graham   +6 more
core   +1 more source

Predicting epilepsy after new onset refractory status epilepticus due to autoimmune encephalitis: The DAME score

Epilepsia, EarlyView.
Abstract Objective This study aimed to identify risk factors and develop a predictive scoring system for autoimmune‐associated epilepsy in subjects with autoimmune encephalitis presenting with new onset refractory status epilepticus (NORSE). Methods This retrospective, multicenter, cohort study included subjects who presented with NORSE at the onset of
Simona Lattanzi, Sara Matricardi, Alberto Vogrig, Giada Pauletto, Margherita Nosadini, Stefano Sartori, Federico Massa, Luana Benedetti, Stefano Meletti, Francesca Bisulli, Elena Freri, Francesca Felicia Operto, Silvia Bozzetti, Sara Mariotto, Simone Beretta, Eleonora Rosati, Elisabetta Cesaroni, Carla Marini, Tiziana Granata, Flavio Villani, Immune Epilepsies Study Group of the Italian League Against Epilepsy, Ruggero Bernabei, Stefania Maria Bova, Silva Cappanera, Luigi Caputi, Edward Cesnik, Francesco Deleo, Lidia Di Vito, Giuseppe D’Orsi, Giovanni Falcicchio, Elisa Fallica, Edoardo Ferlazzo, Lucia Fusco, Matteo Gastaldi, Giada Giovannini, Angela La Neve, Claudio Liguori, Pietro Mattioli, Lorenzo Muccioli, Carlotta Mutti, Angelo Pascarella, Elena Pasini, Daniela Passarelli, Francesca Ragona, Romana Rizzi, Elena Tartara, Valentina Tontini, Alberto Verrotti, Federica Zibordi, Lucia Zinno, Antonio Zito   +50 more
wiley   +1 more source