Results 121 to 130 of about 24,272 (299)

The Impact of Intracerebral Hemorrhage on the Progression of White Matter Hyperintensity

Frontiers in Human Neuroscience, 2018
Objective: The exact relationship between white matter hyperintensity (WMH) and intracerebral hemorrhage (ICH) after ICH remains unclear. In this retrospective study, we investigated whether patients with ICH had more severe WMH progression.Patients and ...
Xuemei Chen, Xin Chen, Yan Chen, Manman Xu, Tingting Yu, Junrong Li   +5 more
doaj   +1 more source

Isolated Corticospinal Tract Lesions as an Early Manifestation of Adrenoleukodystrophy in Children

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Purpose X‐linked adrenoleukodystrophy (ALD) encompasses a wide range of neurological manifestations, classically described as distinct phenotypes including childhood cerebral adrenoleukodystrophy and adult‐onset adrenomyeloneuropathy (AMN).
Elle Winter, Amanda Nagy, Yedda Li, Otto Rapalino, Catherine L. Becker, Joseph Locascio, Camilo Jaimes, Florian Eichler   +7 more
wiley   +1 more source

Ideal Cardiovascular Health and Biomarkers of Subclinical Brain Aging: The Northern Manhattan Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background The American Heart Association Life's Simple 7 metric defines ideal cardiovascular health (CVH) on 7 factors: smoking, diet, physical activity, body mass index, blood sugar, blood pressure, and cholesterol.
Hannah Gardener, Michelle Caunca, Chuanhui Dong, Ying Kuen Cheung, Noam Alperin, Tatjana Rundek, Mitchell S. V. Elkind, Clinton B. Wright, Ralph L. Sacco   +8 more
doaj   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Self‐limited neonatal epilepsy with 2q24.3 duplications: Case series and literature review

Epileptic Disorders, EarlyView.
Abstract Objective To clarify the phenotypic spectrum associated with duplications involving the 2q24.3 region, which includes a cluster of genes encoding sodium channel subunits (SCN1A, SCN2A, SCN3A, SCN7A, and SCN9A). Methods We reviewed our research database for patients with epilepsy and 2q24.3 duplication and performed thorough phenotyping.
Saba Al Rawahi, Kenneth A. Myers
wiley   +1 more source

Models to Identify Small Brain White Matter Hyperintensity Lesions

Applied Sciences
According to the World Health Organization (WHO), peripheral and central neurological disorders affect approximately one billion people worldwide. Ischemic stroke and Alzheimer’s Disease and other dementias are the second and fifth leading causes of ...
Darwin Castillo, María José Rodríguez-Álvarez, René Samaniego, Vasudevan Lakshminarayanan   +3 more
doaj   +1 more source

“Liquid Biopsy” of White Matter Hyperintensity in Functionally Normal Elders

Frontiers in Aging Neuroscience, 2018
Background and Objective: In the aging brain, increased blood-brain barrier (BBB) leakage and white matter hyperintensity (WMH) on MRI are frequently presumed secondary to cerebral small vessel disease (cSVD) or endotheliopathy.
Fanny M. Elahi, Kaitlin B. Casaletto, Marie Altendahl, Adam M. Staffaroni, Evan Fletcher, Teresa J. Filshtein, Maria M. Glymour, Bruce L. Miller, Jason D. Hinman, Charles DeCarli, Edward J. Goetzl, Edward J. Goetzl, Joel H. Kramer   +12 more
doaj   +1 more source

Analysis of Gray Matter Volume (GMV) and White Matter Hyperintensity (WMH) in Ischemic Stroke Patients with Fluid Attenuated Inversion Recovery (FLAIR) Imaging

, 2023
Stroke is a serious health problem faced by almost all over the world. The occurrence of ischemic stroke could affect the gray matter volume (GMV) in the human brain.
Karimah, Fadlilah, Ade Lina Nur, Yueniwati, Yuyun, Noor, Johan Andoyo Effendi   +3 more
core  

Beyond Broca and Wernicke: Epilepsy surgery in the language areas

Epileptic Disorders, EarlyView.
Abstract Epilepsy surgery in language areas is challenged by the intricacies of presurgical workup and surgical planning. In recent decades, the view of language‐related circuitry has shifted from being localized in a few cortical centers to a distributed, dynamically interconnected system, increasing complexity.
Carmen Barba, Alessandro De Benedictis, Veronica Pelliccia, Domenico Tortora, Federico Melani, Alessandro Consales, Domenica Immacolata Battaglia, Elisabetta Cesaroni, Lorenzo Ferri, Alice Noris, Matteo Pugnaghi, Michele Rizzi, Giuseppe Bertini, Flavio Villani, Laura Tassi, on behalf of Commission of Epilepsy Surgery, Italian League against Epilepsy   +16 more
wiley   +1 more source

Clinical use and radiological yield of magnetic resonance fingerprinting in epilepsy

Epilepsia, EarlyView.
Abstract Objective Magnetic resonance fingerprinting (MRF) is a novel paradigm for magnetic resonance imaging (MRI) that efficiently generates multiparametric quantitative tissue property maps with a single acquisition. Its quantitative nature offers many advantages over conventional MRI.
Maksim Parfyonov, Ting‐Yu Su, Joon Yul Choi, Ingmar Blümcke, Ken Sakaie, Spencer Morris, Hiroatsu Murakami, Andreas Alexopoulos, Imad Najm, Dan Ma, Stephen E. Jones, Zhong Irene Wang   +11 more
wiley   +1 more source