Results 111 to 120 of about 24,272 (299)

Prevalence of white matter hyperintensities increases with age

Neural Regeneration Research, 2018
White matter hyperintensities (WMHs) that arise with age and/or atherosclerosis constitute a heterogeneous disorder in the white matter of the brain. However, the relationship between age-related risk factors and the prevalence of WMHs is still obscure. More clinical data is needed to confirm the relationship between age and the prevalence of WMHs.
Feng-Juan Zhuang, Yan Chen, Wen-Bo He, Zhi-You Cai   +3 more
openaire   +3 more sources

Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis

Annals of Neurology, EarlyView.
Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi, Chiara Milano, Laura Marmolejo, Ana Beatriz Serafim, Esther Aguilar, Mar Guasp, Elianet Fonseca, Mateus Mistieri Simabukuro, Raffaele Iorio, Yuki Fukami, Maria Lucia Schmitz Ferreira Santos, Takashi Miwa, Takashi Araga, Yuto Uchida, Masanori Kurihara, Satoshi Okada, Luz Victoria Garcia, Kenichi Kaida, Natalia Spinola Costa da Cunha, Alberto Vogrig, Florian Lamblin, Juna M. de Vries, Livia Almeida Dutra, Romana Höftberger, Maarten J. Titulaer, Jesús Planagumà, Lidia Sabater, Eugenia Martinez‐Hernandez, Thais Armangué, Francesc Graus, Takahiro Iizuka, Josep Dalmau, Marianna Spatola, Anti‐GABAAR encephalitis study group   +33 more
wiley   +1 more source

White matter hyperintensity maps in aging and neurodegenerative diseases

<div>The files contain voxel-wise white matter hyperintensity (WMH) maps for 11 different neurodegenerative disease cohorts from the <em>Canadian</em> Consortium on Neurodegeneration in Aging (<em>CCNA</em>) COMPASS-ND ...
Dadar, Mahsa
core   +1 more source

White matter hyperintensity reduction and outcomes after minor stroke [PDF]

, 2017
Objective: To assess factors associated with white matter hyperintensity (WMH) change in a large cohort after observing obvious WMH shrinkage 1 year after minor stroke in several participants in a longitudinal study. Methods: We recruited participants
Valdés Hernández, Maria Del Carmen, Makin, S.D.J., Maria del Carmen Valdés Hernández, Eleni Sakka, Francesca M. Chappell, Heye, A.K., Muñoz-Maniega, Susana, Muñoz Maniega, Susana; id_orcid, Wardlaw, J.M., Thrippleton, M.J., Staals, Julie, Staals, J., Makin, Stephen D.J., Julie Staals, Chappell, Francesca M., Chappell, F.M., Sakka, Eleni, Thrippleton, Michael J., Makin, Stephen D. J., Joanna M. Wardlaw, Michael J. Thrippleton, Dennis, M.S., Anna K. Heye, Hernandez, M.D.C.V., Dennis, Martin S., Paul A. Armitage, Susana Muñoz-Maniega, Martin S. Dennis, Munoz-Maniega, S., Thrippleton, Michael J.; id_orcid, Heye, Anna K., Kirsten Shuler, Shuler, K., Armitage, P.A., Sakka, E., Armitage, Paul A., Shuler, Kirsten, Stephen D.J. Makin, Hernandez, Maria del Carmen Valdes, Wardlaw, Joanna M.   +39 more
core   +1 more source

Use of Machine Learning to Identify Markers of Risk for Fragile X‐Associated Tremor/Ataxia Syndrome: A Preliminary Analysis

Annals of Neurology, EarlyView.
Objective The objective of this study was to examine whether machine learning has the capacity to prospectively identify and predict the emergence of Fragile X‐associated tremor/ataxia syndrome (FXTAS) among male fragile X premutation carriers (PCs). Methods We explored neuropsychological and motor evaluation metrics, brain magnetic resonance imaging ...
Chitrabhanu Gupta, Angeela Poudel, Jun Yi Wang, Randi Hagerman, Glenda Espinal, Jessica Famula, Andrea Schneider, Flora Tassone, Susan M. Rivera, Chen‐Nee Chuah, David Hessl   +10 more
wiley   +1 more source

Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers

Annals of Neurology, EarlyView.
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang, Sid E. O'Bryant, Robert A. Rissman, Leigh A. Johnson, Meredith N. Braskie, Kristine Yaffe, the HABS‐HD Study Team, Sid E. O'Bryant, Kristine Yaffe, Arthur Toga, Robert Rissman, Leigh Johnson, Meredith Braskie, Kevin King, James R. Hall, Melissa Petersen, Raymond Palmer, Robert Barber, Yonggang Shi, Fan Zhang, Rajesh Nandy, Roderick McColl, David Mason, Bradley Christian, Nicole Phillips, Stephanie Large, Joe Lee, Badri Vardarajan, Monica Rivera Mindt, Amrita Cheema, Lisa Barnes, Mark Mapstone, Annie Cohen, Amy Kind, Ozioma Okonkwo, Raul Vintimilla, Zhengyang Zhou, Michael Donohue, Rema Raman, Matthew Borzage, Michelle Mielke, Beau Ances, Ganesh Babulal, Jorge Llibre‐Guerra, Carl Hill, Rocky Vig   +45 more
wiley   +1 more source

WHITE MATTER HYPERINTENSITY VOLUME AS A BIOMARKER OF OXIDATIVE STRESS IN ACUTE ISCHEMIC STROKE

, 2010
WHITE MATTER HYPERINTENSITY VOLUME AS A BIOMARKER OF OXIDATIVE STRESS IN ACUTE ISCHEMIC STROKE Zachary A. Corbin, Natalia S. Rost, MGH Stroke Service, Department of Neurology, Massachusetts General Hospital; Jeffrey B. Blumberg, Paul E.
Corbin, Zachary Andrew
core  

Impact of long-term white matter hyperintensity changes on mobility and dexterity [PDF]

White matter hyperintensities (WMH), a common feature of cerebral small vessel disease, are related to worse clinical outcomes after stroke. We assessed the impact of white matter hyperintensity changes over 1 year after minor stroke on change in ...
Wiseman, Stewart, Doubal, Fergus N, Locherty, Rachel; id_orcid, Doubal, Fergus N., Barclay, Gayle, Stringer, Michael S., Hewins, Will, Muñoz Maniega, Susana; id_orcid, Valdés Hernández, Maria, Chappell, Francesca M, Clancy, Una; id_orcid, Liu, Xiaodi, Hamilton, Olivia K L, Chappell, Francesca M., Backhouse, Ellen V., Jochems, Angela C C; id_orcid, Jardine, Charlotte, Gerrish, Iona, Sakka, Eleni, Hamilton, Olivia K.L., Thrippleton, Michael J., Backhouse, Ellen V, Muñoz Maniega, Susana, Arteaga, Carmen, Locherty, Rachel, Jardine, Charlotte; id_orcid, Cheng, Yajun, Clancy, Una, Jochems, Angela C.C., Wardlaw, Joanna M, McIntyre, Donna, Kampaite, Agniete, Thrippleton, Michael J; id_orcid, Zhang, Junfang, Jaime Garcia, Daniela, Wardlaw, Joanna M., Stringer, Michael S   +36 more
core   +1 more source

Cerebrospinal Fluid Amyloid‐β Biomarkers Predict Future Hemorrhage in Patients with Cerebral Amyloid Angiopathy

Annals of Neurology, EarlyView.
Objective Accurately predicting future hemorrhagic events in patients with cerebral amyloid angiopathy (CAA) remains a major clinical challenge. It is unknown whether cerebrospinal fluid (CSF) biomarkers of amyloid‐beta (Aβ) pathology are associated with increased hemorrhage risk in this population.
Philipp Arndt, Malte Pfister, Valentina Perosa, Hendrik Mattern, Melis Tas, Lara Holzheimer, Johanna Engel, Marc Dörner, Marwa Al‐Dubai, Cornelia Garz, Eya Khadhraoui, Sebastian J. Müller, Patrick Müller, Sven G. Meuth, Katja Neumann, Stefanie Schreiber   +15 more
wiley   +1 more source

Structural and Functional Imaging of Motor Outcomes in Twins With Perinatal Stroke: A Case Report

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Perinatal arterial ischemic stroke (AIS) affects 1 in 4000 live births. Dystonia, affecting ~20% of children following AIS, is characterized by involuntary muscle contractions and abnormal movements. Why some develop dystonia post AIS, while others do not, remains unclear.
Prisca Hsu, Trish Domi, Cecilia Jobst, Min Sheng, Amanda Robertson, Erum Syed, Pradeep Krishnan, Douglas Cheyne, Nomazulu Dlamini   +8 more
wiley   +1 more source