Results 51 to 60 of about 5,445,938 (234)

White matter microstructure in patients with obsessive–compulsive disorder [PDF]

Journal of Psychiatry & Neuroscience, 2011
Previous diffusion tensor imaging (DTI) studies in patients with obsessive-compulsive disorder (OCD) have reported inconsistent findings, and it is not known whether observed findings are related to abnormalities in axonal structure or myelination.In this DTI study, we investigated fractional anisotropy, as well as axial and radial diffusivity, in 21 ...
Bora, Emre, Harrison, Ben J., Fornito, Alex, Cocchi, Luca, Pujol, Jesus, Fontenelle, Leonardo F., Velakoulis, Dennis, Pantelis, Christos, Yucel, Murat   +8 more
openaire   +6 more sources

White Matter Microstructure and the General Psychopathology Factor in Children [PDF]

Journal of the American Academy of Child & Adolescent Psychiatry, 2020
Co-occurrence of behavioral and emotional problems in childhood is widespread, and previous studies have suggested that this reflects vulnerability to experience a range of psychiatric problems, often termed a general psychopathology factor. However, the neurobiological substrate of this general factor is not well understood.
Alexander Neumann, Ryan L. Muetzel, Benjamin B. Lahey, Marian J. Bakermans-Kranenburg, Marinus H. van IJzendoorn, Vincent W. Jaddoe, Manon H.J. Hillegers, Tonya White, Henning Tiemeier   +8 more
openaire   +3 more sources

Right Fronto-Subcortical White Matter Microstructure Predicts Cognitive Control Ability on the Go/No-go Task in a Community Sample

Frontiers in Human Neuroscience, 2018
Go/no-go tasks are widely used to index cognitive control. This construct has been linked to white matter microstructure in a circuit connecting the right inferior frontal gyrus (IFG), subthalamic nucleus (STN), and pre-supplementary motor area. However,
Kendra E. Hinton, Benjamin B. Lahey, Victoria Villalta-Gil, Brian D. Boyd, Benjamin C. Yvernault, Katherine B. Werts, Andrew J. Plassard, Brooks Applegate, Neil D. Woodward, Bennett A. Landman, David H. Zald   +10 more
doaj   +1 more source

Longitudinal measurement of the developing grey matter in preterm subjects using multi-modal MRI. [PDF]

, 2015
Preterm birth is a major public health concern, with the severity and occurrence of adverse outcome increasing with earlier delivery. Being born preterm disrupts a time of rapid brain development: in addition to volumetric growth, the cortex folds ...
Eaton-Rosen, Z, Alan Bainbridge, Marlow, N, Nicola J. Robertson, Neil Marlow, M. Jorge Cardoso, Eliza Orasanu, Modat, M, Zach Eaton-Rosen, Robertson, NJ, Melbourne, A, Giles S. Kendall, Sebastien Ourselin, Cardoso, MJ, Ourselin, S, Kendall, GS, Orasanu, E, Bainbridge, A, Andrew Melbourne, Marc Modat   +19 more
core   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Anxiety symptoms and puberty interactively predict lower cingulum microstructure in preadolescent Latina girls

Scientific Reports, 2022
Preadolescence is a period of increased vulnerability for anxiety, especially among Latina girls. Reduced microstructure (fractional anisotropy; FA) of white matter tracts between limbic and prefrontal regions may underlie regulatory impairments in ...
Dana E. Glenn, Jenna L. Merenstein, Ilana J. Bennett, Kalina J. Michalska   +3 more
doaj   +1 more source

White matter damage and cognitive impairment after traumatic brain injury [PDF]

, 2010
White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent.
Powell, Jane Hilary, Leech, R, K. M. Kinnunen, Counsell, Serena Jane; id_orcid, Bonnelle, V., Sharp, D. J., Kinnunen, K. M., Hawkins, Peter Charlie; id_orcid, Patel, Maneesh Chandrakant, Patel, MC, M. C. Patel, Sharp, David James, Greenwood, Richard, D. J. Sharp, Hawkins, PC, Leech, R., Patel, M. C., Powell, Jane H., Greenwood, R, J. H. Powell, Counsell, S. J., Sharp, DJ, P. C. Hawkins, Counsell, SJ, Powell, JH, R. Greenwood, Kinnunen, KM, R. Leech, Bonnelle, Valerie, Leech, Robert, V. Bonnelle, Kinnunen, Kirsi Maria, Hawkins, R. C., S. J. Counsell   +33 more
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Hemispheric Asymmetry in the Genetic Overlap between Schizophrenia and White Matter Microstructure

Cyborg and Bionic Systems
White matter microstructure, essential for neural communication, is genetically influenced and often disrupted in schizophrenia. Large-scale genome-wide association studies have identified over 200 genome-wide significant loci for schizophrenia, yet the ...
Yujie Zhang, Mengge Liu, Shaoying Wang, Wanwan Zhang, Haoyang Dong, Qian Qian, Yue Wu, Qian Wu, Jinglei Xu, Ying Zhai, Haolin Wang, Jingchun Liu, Yuxuan Tian, Qi Luo, Xinxing Li, Lining Guo, Fengtan Li, Feng Liu   +17 more
doaj   +1 more source

The microstructural correlates of T₁ in white matter [PDF]

Magnetic Resonance in Medicine, 2015
PurposeSeveral studies have shown strong correlations between myelin content and T1 within the brain, and have even suggested that T1 can be used to estimate myelin content. However, other micro‐anatomical features such as compartment size are known to affect longitudinal relaxation rates, similar to compartment size effects in porous media.MethodsT1 ...
Kevin D, Harkins, Junzhong, Xu, Adrienne N, Dula, Ke, Li, William M, Valentine, Daniel F, Gochberg, John C, Gore, Mark D, Does   +7 more
openaire   +2 more sources