Results 61 to 70 of about 28,175 (279)

White matter microstructure in patients with obsessive–compulsive disorder [PDF]

Journal of Psychiatry & Neuroscience, 2011
Previous diffusion tensor imaging (DTI) studies in patients with obsessive-compulsive disorder (OCD) have reported inconsistent findings, and it is not known whether observed findings are related to abnormalities in axonal structure or myelination.In this DTI study, we investigated fractional anisotropy, as well as axial and radial diffusivity, in 21 ...
Bora, Emre, Harrison, Ben J., Fornito, Alex, Cocchi, Luca, Pujol, Jesus, Fontenelle, Leonardo F., Velakoulis, Dennis, Pantelis, Christos, Yucel, Murat   +8 more
openaire   +6 more sources

Right Fronto-Subcortical White Matter Microstructure Predicts Cognitive Control Ability on the Go/No-go Task in a Community Sample

Frontiers in Human Neuroscience, 2018
Go/no-go tasks are widely used to index cognitive control. This construct has been linked to white matter microstructure in a circuit connecting the right inferior frontal gyrus (IFG), subthalamic nucleus (STN), and pre-supplementary motor area. However,
Kendra E. Hinton, Benjamin B. Lahey, Victoria Villalta-Gil, Brian D. Boyd, Benjamin C. Yvernault, Katherine B. Werts, Andrew J. Plassard, Brooks Applegate, Neil D. Woodward, Bennett A. Landman, David H. Zald   +10 more
doaj   +1 more source

Anxiety symptoms and puberty interactively predict lower cingulum microstructure in preadolescent Latina girls

Scientific Reports, 2022
Preadolescence is a period of increased vulnerability for anxiety, especially among Latina girls. Reduced microstructure (fractional anisotropy; FA) of white matter tracts between limbic and prefrontal regions may underlie regulatory impairments in ...
Dana E. Glenn, Jenna L. Merenstein, Ilana J. Bennett, Kalina J. Michalska   +3 more
doaj   +1 more source

The microstructural correlates of T₁ in white matter [PDF]

Magnetic Resonance in Medicine, 2015
PurposeSeveral studies have shown strong correlations between myelin content and T1 within the brain, and have even suggested that T1 can be used to estimate myelin content. However, other micro‐anatomical features such as compartment size are known to affect longitudinal relaxation rates, similar to compartment size effects in porous media.MethodsT1 ...
Kevin D, Harkins, Junzhong, Xu, Adrienne N, Dula, Ke, Li, William M, Valentine, Daniel F, Gochberg, John C, Gore, Mark D, Does   +7 more
openaire   +2 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Limbic white matter microstructure plasticity reflects recovery from depression

, 2015
BACKGROUND White matter microstructure alterations of limbic and reward pathways have been reported repeatedly for depressive episodes in major depressive disorder (MDD) and bipolar disorder (BD). However, findings during remission are equivocal.
Wiest, Roland, Jones, Derek K., Müller, Thomas Jörg, Walther, Sebastian, Müller, Thomas J., Bracht, Tobias   +5 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

The dyslexia candidate locus on 2p12 is associated with general cognitive ability and white matter structure

, 2012
Independent studies have shown that candidate genes for dyslexia and specific language impairment (SLI) impact upon reading/language-specific traits in the general population.
Newbury, Dianne F, Dianne F Newbury, Dianne F. Newbury, Morris, Andrew P., Pennell, CE, Morris, Andrew P, Monaco, Anthony P, Anthony P. Monaco, Susan Ring, Ring, Susan, Whitehouse, Andrew J.O., Scerri, TS, Juha Kere, Ring Susan, Joel B Talcott, Fahimeh Darki, Hans Matsson, Pennell, Craig E, Whitehouse Andrew J. O., Morris Andrew P., Talcott, JB, Talcott Joel B., Torkel Klingberg, Kere Juha, Kere, Juha, Whitehouse, Andrew J O, Darki, Fahimeh, Monaco, AP, Stein, J, Ring, S, Myriam Peyrard, Joel B. Talcott, Silvia Paracchini, Craig E. Pennell, Qi W Ang, Thomas S. Scerri, Anthony P Monaco, Matsson Hans, Thomas S Scerri, Newbury Dianne F., Stein, John, Andrew P Morris, Ang Qi W., Ang, QW, Monaco, Anthony P., Paracchini, Silvia, Peyrard-Janvid, M, Myriam Peyrard-Janvid, Pennell Craig E., Klingberg, Torkel, John Stein, Ang, Qi W., Kere, J, Scerri Thomas S., Scerri, Thomas S, Pennell, Craig E., Talcott, Joel B., Matsson, Hans, Whitehouse, AJ, Craig E Pennell, Talcott, Joel B, Klingberg Torkel, Morris, Andrew, Peyrard-Janvid, Myriam, Whitehouse, Andrew J. O., Talcott, Joel, Monaco Anthony P., Ang, Qi W, Klingberg, T, Darki Fahimeh, Peyrard-Janvid Myriam, Paracchini, S, Morris, AP, Andrew P. Morris, Qi W. Ang, Stein John, Andrew J. O. Whitehouse, Matsson, H, Andrew J O Whitehouse, Newbury, Dianne F., Darki, F, Newbury, DF, Paracchini Silvia, Thomas S. Scerri, Scerri, Thomas S.   +84 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Neuromodulatory subcortical nucleus integrity is associated with white matter microstructure, tauopathy and APOE status

Nature Communications
The neuromodulatory subcortical nuclei within the isodendritic core (IdC) are the earliest sites of tauopathy in Alzheimer’s disease (AD). They project broadly throughout the brain’s white matter.
Alfie Wearn, Stéfanie A. Tremblay, Christine L. Tardif, Ilana R. Leppert, Claudine J. Gauthier, Giulia Baracchini, Colleen Hughes, Patrick Hewan, Jennifer Tremblay-Mercier, Pedro Rosa-Neto, Judes Poirier, Sylvia Villeneuve, Taylor W. Schmitz, Gary R. Turner, R. Nathan Spreng, PREVENT-AD Research Group   +15 more
doaj   +1 more source