Results 31 to 40 of about 13,623,762 (302)

Brain White Matter Structure and Amyloid Deposition in Black and White Older Adults: The ARIC‐PET Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background White matter abnormalities are a common feature of aging and Alzheimer disease, and tend to be more severe among Black individuals. However, the extent to which white matter abnormalities relate to amyloid deposition, a marker of Alzheimer ...
Keenan A. Walker, Noah Silverstein, Yun Zhou, Timothy M. Hughes, Clifford R. Jack, David S. Knopman, A. Richey Sharrett, Dean F. Wong, Thomas H. Mosley, Rebecca F. Gottesman   +9 more
doaj   +1 more source

White matter differences between healthy young ApoE4 carriers and non-carriers identified with tractography and support vector machines. [PDF]

, 2012
The apolipoprotein E4 (ApoE4) is an established risk factor for Alzheimer's disease (AD). Previous work has shown that this allele is associated with functional (fMRI) changes as well structural grey matter (GM) changes in healthy young, middle-aged and ...
Lamberton, F., Hampel, Harald, Miller, Julia, Rujescu, D., Laurence O'Dwyer, Lamberton, Franck, Prvulovic, David, Matura, S., Scheibe, M., O'Dwyer, L.G., David Prvulovic, O'Dwyer, Laurence, Hampel, H., Franck Lamberton, Dan Rujescu, Harald Hampel, Scheibe, Monika, Julia Miller, Prvulovic, D., Silke Matura, Monika Scheibe, Matura, Silke, Miller, J., Rujescu, Dan, Rujescu Dan, Hampel Harald, O'Dwyer Laurence, Matura Silke, Prvulovic David, Miller Julia, Lamberton Franck, Scheibe Monika   +31 more
core   +2 more sources

Calendar age and puberty-related development of regional gray matter volume and white matter tracts during adolescence [PDF]

, 2021
Background Adolescence is a critical time for brain development. Findings from previous studies have been inconsistent, failing to distinguish the influence of pubertal status and aging on brain maturation.
Parzer, Peter, Schell, Susanne, Ando, Ayaka, Resch, Franz, Koenig, Julian, Brunner, Romuald, Stieltjes, Bram, Delorme, Stefan, Kaess, Michael, Henze, Romy, Romy Henze, Susanne Schell, Bram Stieltjes, Ayaka Ando, Michael Kaess, Stefan Delorme, Franz Resch, Peter Parzer, Romuald Brunner, Julian Koenig   +19 more
core   +2 more sources

Cognitive deficits are associated with frontal and temporal lobe white matter lesions in middle-aged adults living in the community [PDF]

, 2010
The work was supported by the Leverhulme Trust and the British Academy and was funded by NHMRC of Australia Unit Grant No. 973302, Program Grant No. 179805, NHMRC project grant No.
Helen Christensen, Kaarin J Anstey, Burns, R, Richard Burns, Perminder S. Sachdev, Cherbuin, N, Anstey, KJ, Christensen, H, David Bunce, Kaarin J. Anstey, Bunce, D, Sachdev, PS ; https://orcid.org/, Wen, W, Wei Wen, Perminder S Sachdev, Christensen, H ; https://orcid.org/, Nicolas Cherbuin, Sachdev, PS, Bunce, David, Christensen Helen, Burns Richard, Wen, Wei, Cherbuin Nicolas, Sachdev, Perminder S., Burns, Richard, Christensen, Helen, Bunce David, Wen Wei, Anstey Kaarin J., Cherbuin, Nicolas, Anstey, Kaarin, Sachdev Perminder S.   +31 more
core   +1 more source

White matter hyperintensity volume in pre-diabetes, diabetes and normoglycemia [PDF]

BMJ Open Diabetes Research & Care, 2021
Introduction As white matter hyperintensities (WMHs) of the brain are associated with an increased risk of stroke, cognitive decline, and depression, elucidating the associated risk factors is important. In addition to age and hypertension, pre-diabetes and diabetes may play important roles in the development of ...
Sergio Grosu, Roberto Lorbeer, Felix Hartmann, Susanne Rospleszcz, Fabian Bamberg, Christopher L Schlett, Franziska Galie, Sonja Selder, Sigrid Auweter, Margit Heier, Wolfgang Rathmann, Katharina Mueller-Peltzer, Karl-Heinz Ladwig, Annette Peters, Birgit B Ertl-Wagner, Sophia Stoecklein   +15 more
openaire   +6 more sources

White matter damage and cognitive impairment after traumatic brain injury [PDF]

, 2010
White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent.
Powell, Jane Hilary, Leech, R, K. M. Kinnunen, Counsell, Serena Jane; id_orcid, Bonnelle, V., Sharp, D. J., Kinnunen, K. M., Hawkins, Peter Charlie; id_orcid, Patel, Maneesh Chandrakant, Patel, MC, M. C. Patel, Sharp, David James, Greenwood, Richard, D. J. Sharp, Hawkins, PC, Leech, R., Patel, M. C., Powell, Jane H., Greenwood, R, J. H. Powell, Counsell, S. J., Sharp, DJ, P. C. Hawkins, Counsell, SJ, Powell, JH, R. Greenwood, Kinnunen, KM, R. Leech, Bonnelle, Valerie, Leech, Robert, V. Bonnelle, Kinnunen, Kirsi Maria, Hawkins, R. C., S. J. Counsell   +33 more
core   +1 more source

White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms [PDF]

Molecular Psychiatry, 2013
Abnormalities in white-matter (WM) microstructure, as lower fractional anisotropy (FA), have been reported in adolescent-onset bipolar disorder and in youth at familial risk for bipolarity. We sought to determine whether healthy adolescents with subthreshold bipolar symptoms (SBP) would have early WM microstructural alterations and whether those ...
Paillère Martinot, M-L, Lemaitre, H, Artiges, E, Miranda, R, Goodman, R, Penttilä, J, Struve, M, Fadai, T, Kappel, V, Poustka, L, Conrod, P, Banaschewski, T, Barbot, A, Barker, G J, Büchel, C, Flor, H, Gallinat, J, Garavan, H, Heinz, A, Ittermann, B, Lawrence, C, Loth, E, Mann, K, Paus, T, Pausova, Z, Rietschel, M, Robbins, T W, Smolka, M N, Schumann, G, Martinot, J-L   +29 more
openaire   +5 more sources

The spectrum of Ischemia-induced white matter injury varies with age [PDF]

, 2013
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Zammit, Christian, Muscat, Richard, Valentino, Mario   +2 more
core   +1 more source

White matter is increased in the brains of adults with neurofibromatosis 1

Orphanet Journal of Rare Diseases, 2022
Background Neurofibromatosis 1 (NF1) is a rare autosomal dominant disease characterized by increased Schwann cell proliferation in peripheral nerves. Several small studies of brain morphology in children with NF1 have found increased total brain volume ...
Su Wang, Jan M. Friedman, Per Suppa, Ralph Buchert, Victor-Felix Mautner   +4 more
doaj   +1 more source

Brain Structural Alterations, Diabetes Biomarkers, and Cognitive Performance in Older Adults With Dysglycemia

Frontiers in Neurology, 2021
Despite the high risk of dementia in older adults with type 2 diabetes, the neuroanatomical correlates of cognitive dysfunction that are particularly affected by diabetes are not well characterized.
Dae Jong Oh, Dae Jong Oh, Ji-Jung Jung, Seong A. Shin, Hairin Kim, Soowon Park, Bo Kyung Sohn, Bo Kyung Koo, Bo Kyung Koo, Min Kyong Moon, Min Kyong Moon, Yu Kyeong Kim, Jun-Young Lee, Jun-Young Lee   +13 more
doaj   +1 more source