Results 21 to 30 of about 13,623,762 (302)

White matter development in early puberty: a longitudinal volumetric and diffusion tensor imaging twin study.

PLoS ONE, 2012
White matter microstructure and volume show synchronous developmental patterns in children. White matter volume increases considerably during development.
Rachel M Brouwer, René C W Mandl, Hugo G Schnack, Inge L C van Soelen, G Caroline van Baal, Jiska S Peper, René S Kahn, Dorret I Boomsma, H E Hulshoff Pol   +8 more
doaj   +1 more source

White matter volume abnormalities and associations with symptomatology in schizophrenia [PDF]

Psychiatry Research: Neuroimaging, 2010
The cerebral white matter (WM) is critically involved in many bio-behavioral functions impaired in schizophrenia. However, the specific neural systems underlying symptomatology in schizophrenia are not well known. By comparing the volume of all brain fiber systems between chronic patients with DSM-III-R schizophrenia (n=88) and matched healthy ...
Nikolaos, Makris, Larry J, Seidman, Todd, Ahern, David N, Kennedy, Verne S, Caviness, Ming T, Tsuang, Jill M, Goldstein   +6 more
openaire   +2 more sources

Antidepressant treatment normalizes white matter volume in patients with major depression.

PLoS ONE, 2012
ObjectiveTo investigate white matter volume abnormalities in patients with major depression and the effects of antidepressant treatment on white matter volume.MethodMagnetic resonance imaging (MRI) was performed on 32 treatment-naïve depressed patients ...
Ling-Li Zeng, Li Liu, Yadong Liu, Hui Shen, Yaming Li, Dewen Hu   +5 more
doaj   +1 more source

Medial frontal white and gray matter contributions to general intelligence. [PDF]

PLoS ONE, 2014
The medial orbitofrontal cortex (mOFC) and rostral anterior cingulate cortex (rACC) are part of a wider neural network that plays an important role in general intelligence and executive function.
Toshiyuki Ohtani, Paul G Nestor, Sylvain Bouix, Yukiko Saito, Taiga Hosokawa, Marek Kubicki   +5 more
doaj   +1 more source

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. [PDF]

, 2010
Objectives: To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death. Design: Systematic review and meta-analysis.
Debette, S, Markus, H.S., Markus, H S, S. Debette, Debette, Stéphanie, H. S. Markus, Markus, HS   +6 more
core   +1 more source

Depressive symptoms and neuroanatomical structures in community-dwelling women: A combined voxel-based morphometry and diffusion tensor imaging study with tract-based spatial statistics

NeuroImage: Clinical, 2014
Depressive symptoms, even at a subclinical level, have been associated with structural brain abnormalities. However, previous studies have used regions of interest or small sample sizes, limiting the ability to generalize the results.
Yayoi K. Hayakawa, Hiroki Sasaki, Hidemasa Takao, Naoto Hayashi, Akira Kunimatsu, Kuni Ohtomo, Shigeki Aoki   +6 more
doaj   +1 more source

Increase of blood-brain barrier leakage is related to cognitive decline in vascular mild cognitive impairment

BMC Neurology, 2021
Background Blood-brain barrier (BBB) breakdown, as an early biomarker for vascular mild cognitive impairment (vMCI), has only been validated by a few studies.
Man Li, Yue Li, Long Zuo, Wenli Hu, Tao Jiang   +4 more
doaj   +1 more source

Automated measurement of local white matter lesion volume

NeuroImage, 2012
It has been hypothesized that white matter lesions at different locations may have different etiology and clinical consequences. Several approaches for the quantification of local white matter lesion load have been proposed in the literature, most of which rely on a distinction between lesions in a periventricular region close to the ventricles and a ...
Fedde van der Lijn, Benjamin F. J. Verhaaren, Mohammad Arfan Ikram, Stefan Klein 0001, Marleen de Bruijne, Henri A. Vrooman, Meike W. Vernooij, Alexander Hammers, Daniel Rueckert, Aad van der Lugt, Monique M. B. Breteler, Wiro J. Niessen   +11 more
openaire   +4 more sources

APOE ɛ 2 is associated with white matter hyperintensity volume in CADASIL [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2015
Apolipoprotein E ( APOE) increases the risk for Alzheimer’s disease ( ɛ4 allele) and cerebral amyloid angiopathy ( ɛ2 and ɛ4), but its role in small vessel disease (SVD) is debated. Here we studied the effects of APOE on white matter hyperintensity volume (WMHV) in CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and ...
Gesierich, Benno, Opherk, Christian, Rosand, Jonathan, Gonik, Mariya, Malik, Rainer, Jouvent, Eric, Hervé, Dominique, Adib Samii, Poneh, Bevan, Steve, Pianese, Luigi, Silvestri, Serena, DOTTI, MARIA, DE STEFANO, NICOLA, van der Grond, Jeroen, Boon, Elles Mj, Pescini, Francesca, Rost, Natalia, Pantoni, Leonardo, Lesnik Oberstein, Saskia A, FEDERICO, ANTONIO, Ragno, Michele, Markus, Hugh S, Tournier Lasserve, Elisabeth, Chabriat, Hugues, Dichgans, Martin, Duering, Marco, Ewers, Michael   +26 more
openaire   +7 more sources

Depression in small-vessel disease relates to white matter ultrastructural damage, not disability. [PDF]

, 2014
OBJECTIVE: To determine whether cerebral small-vessel disease (SVD) is a specific risk factor for depression, whether any association is mediated via white matter damage, and to study the role of depressive symptoms and disability on quality of life (QoL)
Morris, RG, Brookes, RL, Lawrence, AJ, Morris, Robin G., Lawrence, Andrew J.; id_orcid, Herbert, Vanessa, Herbert, V, Brookes, Rebecca L., Markus, Hugh S., Markus, HS   +9 more
core   +1 more source