Results 1 to 10 of about 3,195 (114)
White matter hyperintensities volume and cognition: A meta-analysis
BackgroundCerebral small vessel disease (CSVD) is prevalent in the elderly and leads to an increased risk of cognitive impairment and dementia. The volume of white matter hyperintensities (WMHs) increases with age, which affects cognition.ObjectiveTo ...
Wenjuan Guo, Jing Shi
doaj +3 more sources
Expansion of the cortical grey matter in evolution has been accompanied by an even faster expansion of the subcortical white matter volume and by folding of the grey matter surface, events traditionally considered to occur homogeneously across mammalian ...
Lissa eVentura-Antunes +2 more
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BackgroundWhite matter hyperintensities (WMH) are a key imaging feature of cerebral small-vessel disease (CSVD). However, there is a lack of standardized methods for determining WMH volume, and the value of total white matter (WM) volume in the ...
Sen Zhang +5 more
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White Matter Lesions and Brain Gray Matter Volume in Cognitively Normal Elders [PDF]
Cerebral white matter lesions (WMLs) reflect small vessel disease, are common in elderly individuals, and are associated with cognitive impairment. We sought to determine the relationships between WMLs, age, gray matter (GM) volume, and cognition in the Cardiovascular Health Study (CHS).
Owen T Carmichael +2 more
exaly +3 more sources
Objective: Longer sleep duration in infancy supports cognitive and affective functioning – likely through effects on brain development. From childhood through old age, there is evidence for a close link between sleep and brain volume.
Katharina Pittner +7 more
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Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity [PDF]
Abstract Apolipoprotein ( APOE ) e4 genotype is an accepted risk factor for accelerated cognitive aging and dementia, though its neurostructural substrates are unclear. The deleterious effects of this genotype on brain structure may increase in magnitude into older age. This
Lyall, Donald M. +13 more
openaire +4 more sources
BackgroundRadiotherapy (RT) and chemotherapy are components of standard multi-modality treatment of high grade gliomas (HGG) aimed at achieving local tumor control.
Jesse D de Groot +4 more
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Association of Low Blood Pressure with White Matter Hyperintensities in Elderly Individuals with Controlled Hypertension [PDF]
Background and Purpose Both hypertension and hypotension increase cerebral white matter hyperintensities. However, the effects of hypotension in individuals with treated hypertension are unknown. We analyzed the association of low blood pressure with the
Jun Sung Kim +8 more
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Reducing the impact of white matter lesions on automated measures of brain gray and white matter volumes [PDF]
AbstractPurpose:To develop an automated lesion‐filling technique (LEAP; LEsion Automated Preprocessing) that would reduce lesion‐associated brain tissue segmentation bias (which is known to affect automated brain gray [GM] and white matter [WM] tissue segmentations in people who have multiple sclerosis), and a WM lesion simulation tool with which to ...
Declan T, Chard +3 more
openaire +2 more sources
The missing role of gray matter in studying brain controllability
Brain controllability properties are normally derived from the white matter fiber tracts in which the neural substrate of the actual energy consumption, namely the gray matter, has been widely ignored.
Hamidreza Jamalabadi +8 more
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