Results 31 to 40 of about 33,638 (255)

Status of Coral Health and Disease in Kessilampe Waters, Kendari, South East Sulawesi

Ilmu Kelautan, 2018
Diseases of coral reef organisms have become a global threat to coral reefs and a major cause of reef deterioration. The presence of coral diseases influence marine resources productivity that interact with coral reefs. The purpose of this research is to
Ratna Diyah Palupi, Rahmadani Rahmadani, Ira Ira   +2 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

The evidence of bacilliform virus a causative agent of white spot syndrome of white shrimp Penaeus merguiensis

Journal of Biological Researches, 2003
The rod-shape virus particles were found in the hyperthrophied nucleus and cytoplasm of diseased white shrimpPenaeus merguiensis naturally infected by White spot syndrome (WSBV).
Hari Suprapto
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

White Spot Syndrome Virus Orf514 Encodes a Bona Fide DNA Polymerase

Molecules, 2011
White spot syndrome virus (WSSV) is the causative agent of white spot syndrome, one of the most devastating diseases in shrimp aquaculture. The genome of WSSV includes a gene that encodes a putative family B DNA polymerase (ORF514), which is 16 ...
Rogerio R. Sotelo-Mundo, Luis G. Brieba, Jesús Hernández, Adriana Muhlia-Almazan, Gloria Yepiz-Plascencia, Aldo A. Arvizu-Flores, Karina D. Garcia-Orozco, Enrique de-la-Re-Vega   +7 more
doaj   +1 more source

Circulating Phylotypes of White Spot Syndrome Virus in Bangladesh and Their Virulence

Microorganisms, 2022
White Spot Syndrome Virus (WSSV) has emerged as one of the most prevalent and lethal viruses globally and infects both shrimps and crabs in the aquatic environment.
Mehedi Mahmudul Hasan, M. Nazmul Hoque, Firoz Ahmed, Md. Inja-Mamun Haque, Munawar Sultana, M. Anwar Hossain   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Immune responses and resistance of white shrimp (Litopenaeus vannamei) fed Probiotic Bacillus sp NP5 and prebiotic honey against White Spot Syndrome Virus infection

Jurnal Akuakultur Indonesia, 2020
White spot disease caused by White Spot Syndrome Virus (WSSV) is the most serious viral disease and has a major impact on the decline in production of white shrimp farm.
Widanarni Widanarni, Dewi Rahmi, Muhamad Gustilatov, Sukenda Sukenda, Diah Ayu Satyari Utami   +4 more
doaj   +1 more source

Shrimp White Spot Syndrome - from Pathology to Pathogenomics

Fish Pathology, 2009
For shrimp with low-level white spot syndrome virus (WSSV, = PRDV) infection, environmental or physiological stresses can trigger replication of the virus and lead to a full-blown outbreak of white spot disease. This review will describe how pathogenomic studies have revealed some of the mechanisms that underlie this aspect of WSSV pathology.
Kuan Fu Liu, Wang-Jing Liu, Guang-Hsiung Kou, Chu-Fang Lo   +3 more
openaire   +2 more sources