In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
Background White Spot Syndrome Virus, a member of the virus family Nimaviridae, is a large dsDNA virus infecting shrimp and other crustacean species. Although limited information is available on the mode of transcription, previous data suggest that WSSV ...
Sandbrink Hans +4 more
doaj +1 more source
Sekuen Asam Amino Anti White Spot Syndrome Virus (Wssv) pada Udang Windu (Penaeus Monodon) [PDF]
This study aimed to determine the amino acid sequencehomology, functional domains, the model predictionof protein structure and characteristics of genesencoding anti WSSV in black tiger shrimp (Penaeusmonodon) originated from Indramayu District ...
Iskandar, I. (Iskandar) +2 more
core
Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from Porcine Respiratory and Reproductive virus infections [PDF]
The Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is the etiological agent of one of the most important swine diseases with a significant economic burden worldwide.
Borrás, Francesc E. +6 more
core +4 more sources
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Import risk analysis: A case study of white shrimp in Thailand [PDF]
As the culture industry of black tiger shrimp in Thailand has encountered several problems causing unsuccessful shrimp culture over decades, a new non-indigenous marine species, i.e.
Supamattaya, K. +3 more
doaj
Controlling risks of pathogen transmission by flies on organic pig farms - A review [PDF]
Fly prevention and control on animal production units is necessary to prevent the transmission of pathogens that could affect animal and human health and the maintenance of good hygiene.
Kijlstra, Prof dr A +2 more
core
Histopathology of Y-organ in Indian white shrimp Fenneropenaeus indicus, experimentally infected with white spot syndrome virus [PDF]
Histopathology of Y-organ (moulting gland) in Indian white shrimp Fenneropenaeus indicus was studied after challenging the shrimp with virulent white spot syndrome virus (WSSV).
Alavandi, S V +4 more
core +1 more source
White Spot Syndrome Virus in cultured shrimp: A review
Shrimp is one of the main aquaculture species in the world. Different viruses affect them, which causes serious mortality to economically important species, such as Penaeus monodon, Litopenaeus vannamei and L. stylirostris, among others. White spot syndrome virus or WSSV is a highly lethal, stress-dependent virus, which belongs to the family ...
Jesús Genaro Sánchez-Martínez +2 more
openaire +1 more source
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang +5 more
wiley +1 more source

