Results 81 to 90 of about 4,888,022 (292)

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Immunization of Shrimp by Irradiated Vibrio Paraheamolyticus Against White Spot Syndrome Virus [PDF]

مجله علوم و فنون هسته‌ای, 2016
Shrimp farming industry is of significant importance to the economy, particularly in the south area of Iran. However, this industry faces with various challenges such as viral and bacterial disaeses. The losses due to Vibriosis and white spot syndrome in
M Heidarieh, F Motamedi Sedeh, M Soltani, M Afsharnasab, S Rajabifar   +4 more
doaj  

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Nonlinear Law Spectral Technique to Analyze White Spot Syndrome Virus. [PDF]

, 2010
In this paper a novel spectral technique based on KLaw Fourier nonlinear methodology is developed to classify White Spot Syndrome Virus inclusion bodies found in images from infected shrimp tissue samples. Shrimp culture is expanding in the world due
Bueno Ibarra, Mario Alonso, Álvarez-Borrego, Josué, Chávez Sánchez, María Cristina   +2 more
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Mud crab susceptibility to disease from white spot syndrome virus is species-dependent

BMC Research Notes, 2010
Background Based on a report for one species (Scylla serrata), it is widely believed that mud crabs are relatively resistant to disease caused by white spot syndrome virus (WSSV).
Sritunyalucksana Kallaya, Krittanai Chartchai, Udompetcharaporn Attasit, Mangkalanan Seksan, Somboonna Naraporn, Flegel TW   +5 more
doaj   +1 more source

Produção de um anticorpo policlonal contra a proteína viral [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Agrárias. Curso de Engenharia de Aquicultura.A carcinicultura mundial vem enfrentando sérios problemas de ordem sanitária, especialmente de origem viral, sendo a principal ...
Bona, Ananice
core  

Interaction of white spot syndrome virus VP26 protein with actin

Virology, 2005
VP26 protein, the product of the WSV311 gene of white spot syndrome virus (WSSV), is one of major structural proteins of virus. In this study, when purified virions were treated with Triton X-100 detergent, VP26 protein was present in both the envelope and the nucleocapsid fraction.
Xie, XX, Yang, F
openaire   +3 more sources

Quantitative analysis of the dose–response of white spot syndrome virus in shrimp [PDF]

Journal of Fish Diseases, 2018
AbstractWhite spot syndrome virus (WSSV) is an important cause of mortality and economic losses in shrimp farming. Although WSSV‐induced mortality is virus dose dependent and WSSV infection does not necessarily lead to mortality, the relationships between virus‐particle dose, infection and mortality have not been analysed quantitatively.
Ngo, Thuy T.N., Senior, Alistair M., Culina, Antica, Santos, Eduardo S.A., Vlak, Just M., Zwart, Mark P.   +5 more
openaire   +5 more sources

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source