Results 71 to 80 of about 4,888,022 (292)

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

open access: yesAdvanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian   +12 more
wiley   +1 more source

Cluster Management to Prevent Transmision of White Spot Syndrome Virus in Extensive Giant Tiger Shrimp Farming (Manajemen Klaster Tambak Udang Windu Untuk Mencegah Penularan Virus White Spot Syndrome)

open access: yesIlmu Kelautan, 2013
Telah dilakukan kajian terhadap efektifitas managemen model klaster dengan tambak non-udang sebagai tambak penyanggah untuk mencegah transmisi penyakit bercak putih viral (WSSV) pada budidaya udang windu skala tradisional.
Arief Taslihan   +2 more
doaj   +1 more source

Análise de polimorfismos de nucleotídeos únicos (SNPs) do gene HSP70 em populações de litopenaeus vannamei comercializadas no Brasil [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Aqüicultura, Florianópolis, 2014.O objetivo do trabalho foi estudar a diversidade genética do gene HSP70 através da análise de SNPs
Ferreira Júnior, Augusto Luiz
core  

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

ASSESSING PATHOGENESIS OF THE WHITE SPOT SYNDROME VIRUS (WSSV) IN THE WHITELEGED SHRIMP (LITOPENAEUS VANNAMEI) Page 1-8

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2007
The pathogenesis of the white spot syndrome virus (WSSV) was studied experimentally with challenge exposure of one hundred post larvae Litopenaeus vannamei each aged 40 days. The shrimp L.
M. Afsharnasab; A. Dashtiannasab; V. Yeganeh
doaj  

VP19 is important for the envelope coating of white spot syndrome virus

open access: yesVirus Research, 2019
VP19 is a major envelope protein of white spot syndrome virus (WSSV), an important pathogen of farmed shrimp. However, the exact function of VP19 in WSSV assembly and infection is unknown. To understand the function of VP19, the gene was knocked down by RNA interference.
Li, Li   +4 more
openaire   +2 more sources

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Functional analysis of the orf390 gene of the White Spot Syndrome Virus

open access: yesVirus Research, 2010
orf390 (WSSV449) is a novel apoptosis inhibitor gene in the genome of the White Spot Syndrome Virus (WSSV). In the present study, we focus on the function of orf390 gene. Stable expression of orf390 prevented SF9 insect cells from undergoing actinomycin D-induced apoptosis.
Feng, Yan   +4 more
openaire   +2 more sources

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Clonagem e expressão de um fragmento recombinante da proteína de 28 KDa do vírus da síndrome da mancha branca (WSSV) de camarões [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2009O vírus da síndrome da mancha branca (WSSV) é o agente infeccioso que trouxe maiores prejuízos ...
Braünig, Patrícia
core  

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