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Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak +7 more
wiley +1 more source
Mycoplasma pneumoniae‐Induced Rash and Mucositis: Clinicopathologic Characterization of 11 Cases
Journal of Cutaneous Pathology, Volume 53, Issue 3, Page 276-283, March 2026.ABSTRACT Background Mycoplasma pneumoniae ‐induced rash and mucositis (MIRM) is a mucocutaneous eruption affecting children and young adults with respiratory tract or clinically occult infection by M. pneumoniae . Mucosal involvement is often robust and may raise concern for Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). Histopathologic
Margaret Lang Houser +5 more
wiley +1 more source
International Journal of Dermatology, Volume 65, Issue 3, Page 456-463, March 2026.ABSTRACT Grzybowski's generalized eruptive keratoacanthoma (GEKA) is a rare variant of keratoacanthomas, characterized by hundreds to thousands of lesions, accompanied by pruritus, mucosal involvement, and comorbidities. Our aim was to analyze the clinical presentation, associated comorbidities, treatment strategies, and outcomes of GEKA.
Nicholas Florin Kormos +6 more
wiley +1 more source
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Cellular responses in crustaceans under white spot syndrome virus infection
Fish & Shellfish Immunology, 2023Innate immunity plays the most important system responsible for protecting crustaceans against invading pathogens. White spot syndrome virus (WSSV) is considered a serious pathogen in crustaceans with high cumulative mortality and morbidity in infected animals.
Ngoc Tuan Tran +6 more
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Ultrastructure analysis of white spot syndrome virus (WSSV)
Archives of Virology, 2019In this study, two aspects of the ultrastructure of white spot syndrome virus (WSSV) were identified: (i) The virus nucleocapsids were disassembled, and transmission electron microscopy (TEM) image analysis confirmed that the nucleocapsids were composed of stacked ring segments rather than the usual helix system, with each ring segment consisting of ...
Li Li, Yongcong Hong, Da Huo, Pumo Cai
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Genetic variation among isolates of White spot syndrome virus
Archives of Virology, 2004White spot syndrome virus (WSSV), member of a new virus family called Nimaviridae, is a major scourge in worldwide shrimp cultivation. Geographical isolates of WSSV identified so far are very similar in morphology and proteome, and show little difference in restriction fragment length polymorphism (RFLP) pattern.
Marks, H. +3 more
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White spot syndrome virus (WSSV) interaction with crayfish haemocytes
Fish & Shellfish Immunology, 2006WSSV particles were detected in separated granular cells (GCs) and semigranular cells (SGCs) by in situ hybridisation from WSSV-infected crayfish and the prevalence of WSSV-infected GCs was 5%, whereas it was 22% in SGCs. This indicates that SGCs are more susceptible to WSSV and that this virus replicated more rapidly in SGCs than in GCs and as a ...
Pikul, Jiravanichpaisal +3 more
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