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Shrimp SIRT4 promotes white spot syndrome virus replication
Fish & Shellfish ImmunologyIn WSSV pathogenesis, the molecular mechanisms and the key host factors that regulate the viral replication and morphogenesis remain unclear. However, like most viruses, WSSV is known to induce metabolic reprogramming in several metabolic pathways including the host glutamine metabolism, and several recent reports have suggested that the sirtuins SIRT3,
Yu Kent Tan +5 more
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Thioredoxin of Litopenaeus vannamei facilitated white spot syndrome virus infection
Journal of Invertebrate Pathology, 2015Thioredoxin (TRX), a major intracellular antioxidant, has a wide range of biological functions. It was up-regulated and targeted by WSSV. However, the relevance of TRX with WSSV infection and signaling pathway remains largely unknown. Sequence analysis indicated that TRX might interact with the WSSV030 (VP362) and WSSV454 (thymidine kinase-thymidylate ...
Peng-fei, Liu +3 more
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Dietary quercetin protects Cherax quadricarinatus against white spot syndrome virus infection
Journal of Invertebrate Pathology, 2023Quercetin is a plant flavonoid with a molecular formula C15H10O7. It has antioxidant, anti-inflammatory, antibacterial, and anti-apoptotic effects in animals. We used red claw crayfish (Cherax quadricarinatus) infected with white spot syndrome virus (WSSV) to investigate quercetin's effects on innate immunity of crustaceans.
Jing, Gong +3 more
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Silencing shrimp white spot syndrome virus (WSSV) genes by siRNA
Antiviral Research, 2007White spot syndrome virus (WSSV) is a major shrimp pathogen causing large economic losses all over the world. So far, however, there is no efficient approach to control this virus. RNA interference (RNAi), which has been applied to silence virus genes in eukaryotic organisms.
Xu, Jianyang, Han, Fang, Zhang, Xiaobo
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Shrimp MyD88 responsive to bacteria and white spot syndrome virus
Fish & Shellfish Immunology, 2013The myeloid differentiation factor 88 (MyD88) is an important adapter protein which links members of the toll-like receptor (TLR) to the downstream components to activate related signaling pathways. In the present study, a MyD88 homolog (FcMyD88) was cloned from penaeid shrimp Fenneropenaeus chinensis. The ORF of FcMyD88 consisted of 1434 bp encoding a
Rong, Wen +4 more
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Proteomic analyses of the shrimp white spot syndrome virus
Virologica Sinica, 2008White spot syndrome virus (WSSV), a unique member within the virus family Nimaviridae, is the most notorious aquatic virus infecting shrimp and other crustaceans and has caused enormous economic losses in the shrimp farming industry worldwide. Therefore, a comprehensive understanding of WSSV morphogenesis, structural proteins, and replication is ...
Yan-wei Tan, Zheng-li Shi
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Tolerance of Macrobrachium rosenbergii to white spot syndrome virus
Aquaculture, 2000The susceptibility of Macrobrachium idella, M. lamerrae and M. rosenbergii to white spot syndrome virus (WSSV) was tested by immersion challenge, oral route and intramuscular injection. Their susceptibility to WSSV was compared with that of Penaeus indicus and P. monodon. The WSSV caused 43.3% and 53.3% mortality in M. lamerrae and M.
A.S Sahul Hameed +2 more
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Protein expression in white spot syndrome virus infected Penaeus monodon fabricius
Virus Research, 2005White spot syndrome virus (WSSV) is the causative agent of the white spot disease of shrimp. Penaeus monodon were captured from Muttukadu Estuary in Chennai, India, transported to the laboratory and maintained in an aerated system with continuous water circulation-biofiltration. WSSV-free P.
P, Rameshthangam, P, Ramasamy
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