Background: Brain metastasis increases morbidity and mortality in cancer patients. This study was undertaken to compare tumor response and treatment-related toxicities in patients treated with orally administered thalidomide concomitantly with whole brain radiotherapy to whole brain radiotherapy alone in brain ...
Deiwakor, Chyrmang +5 more
openaire +2 more sources
Erlotinib in patients with previously irradiated, recurrent brain metastases from non-small cell lung cancer: Two case reports [PDF]
Background: With the current improvements in primary lung care, the long-term control of brain metastases becomes a clinical challenge. No established therapeutic approaches exist for cranial relapse after response to previous radiotherapy and systemic ...
Pawel, Joachim +3 more
core +1 more source
Automated field‐in‐field whole brain radiotherapy planning
AbstractPurposeWe developed and tested an automatic field‐in‐field (FIF) solution for whole‐brain radiotherapy (WBRT) planning that creates a homogeneous dose distribution by minimizing hotspots, resulting in clinically acceptable plans.MethodsA configurable auto‐planning algorithm was developed to automatically generate FIF WBRT plans independent of ...
Huang, Kai +7 more
openaire +2 more sources
Whole brain radiotherapy for brain metastasis
Whole brain radiotherapy (WBRT) is a mainstay of treatment in patients with both identifiable brain metastases and prophylaxis for microscopic disease. The use of WBRT has decreased somewhat in recent years due to both advances in radiation technology, allowing for a more localized delivery of radiation, and growing concerns regarding the late toxicity
McTyre, Emory +2 more
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Hypofractionated stereotactic radiotherapy in combination with whole brain radiotherapy for brain metastases [PDF]
The efficacy and toxicity of hypofractionated stereotactic radiotherapy (HSRT) in combination with whole brain radiotherapy (WBRT), for the treatment of 1-4 brain metastases, using a non invasive fixation of the skull, was investigated.Between 04/2001 and 01/2006 30 patients with 44 brain metastases underwent irradiation.
Giubilei, Cesare +4 more
openaire +4 more sources
Integration of chemotherapy into current treatment strategies for brain metastases from solid tumors
Patients with brain metastases represent a heterogeneous group where selection of the most appropriate treatment depends on many patient- and disease-related factors.
Thamm Reinhard +4 more
doaj +1 more source
Analysis of prognostic factors in patients with brain metastases affecting survival
Introduction Brain metastases (BM) are associated with dismal prognosis as they cause significant morbidity and affect the quality of life of patients.
Sweety Gupta +9 more
doaj +1 more source
Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer:5-year results for local control and overall survival from the TARGIT-a randomised trial [PDF]
Background: The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam radiotherapy (EBRT) for breast cancer.
Tobias, Jeffrey S. +36 more
core +1 more source
Recently, a review on a pertinent issue of repeat whole-brain radiotherapy (re-WBRT) for recurring brain metastases was published [...
Lucyna Kępka
core +1 more source
Retrospective evaluation of radiotherapy techniques in the management of patients with brain metastasis: A single-center Experience [PDF]
Introduction: The aim of this study was to evaluate the demographic characteristics and radiotherapy schedules of patients for whom palliative radiotherapy for brain metastasis was administered.
Fatih Goksel, Yasemin Guzle Adas
doaj +1 more source

