Results 11 to 20 of about 133,285 (252)

Vaccination Against Tuberculosis With Whole-Cell Mycobacterial Vaccines [PDF]

Journal of Infectious Diseases, 2016
Live attenuated and killed whole-cell vaccines (WCVs) offer promising vaccination strategies against tuberculosis. A number of WCV candidates, based on recombinant bacillus Calmette-Guerin (BCG), attenuated Mycobacterium tuberculosis, or related mycobacterial species are in various stages of preclinical or clinical development.
Scriba, Thomas J., Kaufmann, Stefan H. E., Lambert, Paul Henri, Sanicas, Melvin, Martin, Carlos, Neyrolles, Olivier   +5 more
openaire   +6 more sources

Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cells

OncoImmunology, 2023
Among cancer immunotherapy, which has received great attention in recent years, cancer vaccines can potentially prevent recurrent tumors by using the exquisite power and specificity of the immune system.
Nabeel Kajihara, Yoshino Tanaka, Riko Takeuchi, Takuto Kobayashi, Masafumi Tanji, Tsukasa Ataka, Shiho Nakano, Taisho Yamada, Akinori Takaoka, Yoshinori Hasegawa, Ken-Ichiro Seino, Haruka Wada   +11 more
doaj   +1 more source

EFFECT OF TARGETED INHIBITION OF Myc ON IMMUNOGENICITY OF LEWIS LUNG CARCINOMA WHOLE-CELL VACCINE IN MICE [PDF]

精准医学杂志, 2023
Objective To prepare a whole-cell vaccine for murine Lewis lung carcinoma (LLC), and to investigate the role of this vaccine in enhancing the anti-LLC ability of immune system in C57BL/6N mice. Methods TCGA database was used to analyze the changes in the
ZHANG Xueming, WANG Hui, QIAN Dongmeng, WANG Bin
doaj   +1 more source

Characterization of Coxiella burnetii Dugway Strain Host-Pathogen Interactions In Vivo

Microorganisms, 2022
Coxiella burnetii is a Gram-negative, intracellular bacterium that causes the zoonosis Q fever. Among the many natural isolates of C. burnetii recovered from various sources, the Dugway group exhibits unique genetic characteristics, including the largest
Mahelat Tesfamariam, Picabo Binette, Diane Cockrell, Paul A. Beare, Robert A. Heinzen, Carl Shaia, Carrie Mae Long   +6 more
doaj   +1 more source

Bordetella pertussis whole cell immunization protects against Pseudomonas aeruginosa infections

npj Vaccines, 2022
Whole cell vaccines are complex mixtures of antigens, immunogens, and sometimes adjuvants that can trigger potent and protective immune responses. In some instances, such as whole cell Bordetella pertussis vaccination, the immune response to vaccination ...
Catherine B. Blackwood, Margalida Mateu-Borrás, Emel Sen-Kilic, Gage M. Pyles, Sarah Jo Miller, Kelly L. Weaver, William T. Witt, Annalisa B. Huckaby, Jason Kang, Courtney E. Chandler, Robert K. Ernst, F. Heath Damron, Mariette Barbier   +12 more
doaj   +1 more source

Protective Efficacy of Novel Oral Biofilm Vaccines against Lactococcus garvieae Infection in Mullet, Mugil cephalus

Vaccines, 2021
Lactococcus garvieae (L. garvieae) is an important pathogen that causes enormous economic losses in both marine and freshwater aquaculture. At present, antibiotics are the only option for farmers to reduce the losses caused by L. garvieae.
Feng-Jie Su, Meei-Mei Chen
doaj   +1 more source

Protective efficacy of a whole cell pertussis vaccine [PDF]

BMJ, 1988
A trial of the efficacy of a plain whole cell pertussis vaccine was conducted in Sweden. In this non-blinded trial 525 infants aged 2 months who were born on days with an even number received three doses of vaccine one month apart and 615 infants of the same age who were born on days with an odd number were enrolled as controls. During the 18 months of
M, Blennow, P, Olin, M, Granström, R H, Bernier   +3 more
openaire   +2 more sources

Rethinking Antigen Source: Cancer Vaccines Based on Whole Tumor Cell/tissue Lysate or Whole Tumor Cell

Advanced Science, 2023
Cancer immunotherapies have improved human health, and one among the important technologies for cancer immunotherapy is cancer vaccine. Antigens are the most important components in cancer vaccines.
Lu Diao, Mi Liu
doaj   +1 more source

Respiratory Immunization With a Whole Cell Inactivated Vaccine Induces Functional Mucosal Immunoglobulins Against Tuberculosis in Mice and Non-human Primates

Frontiers in Microbiology, 2020
Vaccination through the natural route of infection represents an attractive immunization strategy in vaccinology. In the case of tuberculosis, vaccine delivery by the respiratory route has regained interest in recent years, showing efficacy in different ...
Nacho Aguilo, Nacho Aguilo, Santiago Uranga, Santiago Uranga, Elena Mata, Elena Mata, Raquel Tarancon, Raquel Tarancon, Ana Belén Gómez, Ana Belén Gómez, Dessislava Marinova, Dessislava Marinova, Isabel Otal, Isabel Otal, Marta Monzón, Juan Badiola, Dolores Montenegro, Eugenia Puentes, Esteban Rodríguez, Richard A. W. Vervenne, Claudia C. Sombroek, Frank A. W. Verreck, Carlos Martín, Carlos Martín, Carlos Martín   +24 more
doaj   +1 more source

Seroprevalence of Antibodies to Pertussis Toxin among Different Age Groups in Thailand after 37 Years of Universal Whole-Cell Pertussis Vaccination. [PDF]

PLoS ONE, 2016
Despite the high coverage of prophylactic vaccine against Bordetella pertussis infection in many countries for more than three decades, pertussis remains a common vaccine-preventable disease. Infections have been detected more commonly in countries using
Nasamon Wanlapakorn, Varisara Ngaovithunvong, Thanunrat Thongmee, Preeyaporn Vichaiwattana, Sompong Vongpunsawad, Yong Poovorawan   +5 more
doaj   +1 more source