Results 21 to 30 of about 133,285 (252)
Vaccines, 2022 The emergence of drug-resistant gonorrhea infections worldwide combined with the lack of a vaccine is alarming. We prepared a novel microparticulate (MP) vaccine formulation using whole-cell inactivated Neisseria gonorrhoeae as the vaccine antigen, with ...
Priyal Bagwe +4 more
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Injectable cryogel-based whole-cell cancer vaccines [PDF]
Nature Communications, 2015 A biomaterial-based vaccination system that uses minimal extracorporeal manipulation could provide in situ enhancement of dendritic cell (DC) numbers, a physical space where DCs interface with transplanted tumour cells, and an immunogenic context. Here we encapsulate GM-CSF, serving as a DC enhancement factor, and CpG ODN, serving as a DC activating ...
Bencherif, Sidi +10 more
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Memory immune responses against pandemic (H1N1) 2009 influenza virus induced by a whole particle vaccine in cynomolgus monkeys carrying Mafa-A1*052:02. [PDF]
PLoS ONE, 2012 We made an H1N1 vaccine candidate from a virus library consisting of 144 ( = 16 HA×9 NA) non-pathogenic influenza A viruses and examined its protective effects against a pandemic (2009) H1N1 strain using immunologically naïve cynomolgus macaques to ...
Masahiko Arikata +21 more
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Биопрепараты: Профилактика, диагностика, лечение, 2021 Some scientific publications contain data suggesting the “return” or “resurgence” of pertussis. Prevention and elimination of pertussis can only be achieved by extensive immunisation of susceptible populations with a highly effective vaccine.
I. A. Alekseeva +2 more
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An infant who suffered seizures many times after pentavalent vaccination: A case report
İstanbul Kuzey Klinikleri, 2020 Although rare, serious adverse effects may be seen after vaccination. Especially, the whole-cell pertussis vaccine has been held responsible for neurological side effects, as the most important problem in vaccination.
Meryem Erat Nergiz +4 more
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Whole Cell Vaccines—Past Progress and Future Strategies [PDF]
Seminars in Oncology, 2012 Cancer vaccines have shown success in curing tumors in preclinical models. Accumulating evidence also supports their ability to induce immune responses in patients. In many cases, these responses correlate with improved clinical outcomes. However, cancer vaccines have not yet demonstrated their true potential in clinical trials.
Bridget P, Keenan, Elizabeth M, Jaffee
openaire +2 more sources
Proteomics of Bordetella pertussis whole-cell and acellular vaccines [PDF]
BMC Research Notes, 2019 Bordetella pertussis is the etiological agent of whooping cough, a bacterial infection of especially children, which may be fatal without treatment. In frame of studies to investigate putative effects of vaccination on host-pathogen interaction and clonal distribution of strains, in addition to Corynebacterium diphtheriae and Clostridium tetani toxoid ...
Jens Möller +2 more
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Fructose potentiates the protective efficiency of live Edwardsiella tarda cell vaccine
Frontiers in Immunology, 2023 Vaccination is an effective measure to prevent infection by pathogens. Live vaccines have higher protective efficacy than inactivated vaccines. However, how live vaccines interact with the host from a metabolic perspective is unknown.
Chao Wang +5 more
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PLoS ONE, 2015 BackgroundA novel avian H7N9 virus with a high case fatality rate in humans emerged in China in 2013. We evaluated the immunogenicity and protective efficacy of a candidate Vero cell culture-derived whole-virus H7N9 vaccine in small animal models ...
Walter Wodal +13 more
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Frontiers in Immunology, 2023 IntroductionThe combination of Myc-suppressed whole tumor cells with checkpoint inhibitors targeting CTLA-4 and PD-L1 generates a potent therapeutic cancer vaccine in a mouse neuroblastoma model. As immunotherapies translate from pre-clinical to clinical
Xiaofang Wu +8 more
doaj +1 more source