Results 131 to 140 of about 97,288 (294)
Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation
Advanced Science, EarlyView.This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun +9 morewiley +1 more sourceEvolutionary restoration of fertility in an interspecies hybrid yeast, by whole-genome duplication after a failed mating-type switch.
PLoS Biology, 2017 Many interspecies hybrids have been discovered in yeasts, but most of these hybrids are asexual and can replicate only mitotically. Whole-genome duplication has been proposed as a mechanism by which interspecies hybrids can regain fertility, restoring ...Raúl A Ortiz-Merino, Nurzhan Kuanyshev, Stephanie Braun-Galleani, Kevin P Byrne, Danilo Porro, Paola Branduardi, Kenneth H Wolfe +6 moredoaj +1 more sourceThe house spider genome reveals an ancient whole-genome duplication during arachnid evolution
BMC Biology, 2017 Background The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in some chelicerate Evelyn E. Schwager, Prashant P. Sharma, Thomas Clarke, Daniel J. Leite, Torsten Wierschin, Matthias Pechmann, Yasuko Akiyama-Oda, Lauren Esposito, Jesper Bechsgaard, Trine Bilde, Alexandra D. Buffry, Hsu Chao, Huyen Dinh, HarshaVardhan Doddapaneni, Shannon Dugan, Cornelius Eibner, Cassandra G. Extavour, Peter Funch, Jessica Garb, Luis B. Gonzalez, Vanessa L. Gonzalez, Sam Griffiths-Jones, Yi Han, Cheryl Hayashi, Maarten Hilbrant, Daniel S. T. Hughes, Ralf Janssen, Sandra L. Lee, Ignacio Maeso, Shwetha C. Murali, Donna M. Muzny, Rodrigo Nunes da Fonseca, Christian L. B. Paese, Jiaxin Qu, Matthew Ronshaugen, Christoph Schomburg, Anna Schönauer, Angelika Stollewerk, Montserrat Torres-Oliva, Natascha Turetzek, Bram Vanthournout, John H. Werren, Carsten Wolff, Kim C. Worley, Gregor Bucher, Richard A. Gibbs, Jonathan Coddington, Hiroki Oda, Mario Stanke, Nadia A. Ayoub, Nikola-Michael Prpic, Jean-François Flot, Nico Posnien, Stephen Richards, Alistair P. McGregor +54 moredoaj +1 more sourceFish-specific genome duplication
, 2006 The ray-finned fishes are the most diverse and successful within the vertebrates and their genomes vary widely in size. Previous studies suggested that two rounds of genome duplications have been involved in vertebrate evolution.Gui Jian-fang, Zhou Li, Gui Jian-fang (jfgui@ihb.ac.cn), Chinese Acad Sci, State Key Lab Freshwater Ecol and Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China, Wang Yang +4 morecore Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression
Advanced Science, EarlyView.THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang +10 morewiley +1 more source8p23.1 duplication syndrome differentiated from copy number variation of the defensin cluster at prenatal diagnosis in four new families
, 2010 Background: the 8p23.1 duplication syndrome and copy number variation of the 8p23.1 defensin gene cluster are cytogenetically indistinguishable but distinct at the molecular level.Emma-Jane Taylor, Liehr, Thomas, Susanne Morlot, Joana Trindade, Ocraft, Kevin, Ana I Paramos, Viv K Maloney, Paramos Ana I, Bunyan Dave, Curtis, Merryl, Claudia Alves, Merryl Curtis, Maloney, Viv K., Dermitzel Anette, Bunyan, Dave, Denise Robinson, Dermitzel, Anette, Thomas Liehr, Alves Claudia, John CK Barber, Kevin Ocraft, Taylor, Emma-Jane, Clare Cooper, Alves, Claudia, Taylor Emma-Jane, Anette Dermitzel, Curtis Merryl, Ocraft Kevin, Barber John CK, Cooper Clare, Paramos, Ana I., Cooper, Clare, Liehr Thomas, Barber, John C.K., Robinson, Denise, Trindade Joana, Morlot, Susanne, Morlot Susanne, Robinson Denise, Maloney Viv K, Dave Bunyan, Trindade, Joana +41 morecore +1 more sourceMulti-Platform Next-Generation Sequencing of the Domestic Turkey (Meleagris gallopavo): Genome Assembly and Analysis [PDF]
, 2010 A synergistic combination of two next-generation sequencing platforms with a detailed comparative BAC physical contig map provided a cost-effective assembly of the genome sequence of the domestic turkey (Meleagris gallopavo).Kent M Reed, Zhang, Liqing, Zhang Hong-Bin, Kim, Heebal, Rami A Dalloul, Langenberger, D., Scheuring, C., Evans, Clive, Crooijmans, R. P. M. A., Lee, Mi-Kyung, Lee, Taeheon, Kim, H., Evans, C., Nefedov Mikhail, Mane, Shrinivasrao, Frederickson, K. M., Crooijmans, Richard P. M. A., Williams, K. P., Marz, M., Liqing Zhang, Paul Flicek, Dodgson, J. B., David Langenberger, Smith Jacqueline, Dodgson, J. B., Flicek, Paul, Dong, J. J., Jiang, A., Kim, K. W., Zhang Yang, Kim, H., Manja Marz, Long, J. A., Williams, Kelly P., Schatz Michael C., Julie A. Long, Raineri Emanuele, Folkerts, O., Otto Folkerts, Zhang, H.-B., McElroy, A. P., Zhang, L., Delany, Mary E., Long, Julie A., Kelly P. Williams, McElroy Audrey P., Paton, I. R., Beal Kathryn, de Jong, P., Vilella, A. J., Yorke, J. A., Vilella Albert J., Salzberg, Steven L., Harkins Tim T., Megens, H.-J., Kim Sungwon, Crasta Oswald, Burt, David W., Bouffard Pascal, Schroeder, S., Albert J. Vilella, Burt, D. W., Liliana Florea, Mane Shrinivasrao, Carl J. Schmidt, Modise, Thero, Harkins, T. T., Jacqueline Smith, Frederickson, Karin M., Kristal Cooper, Stadler Peter F., Martien A. M. Groenen, Steven L. Salzberg, van Tassell, C. P., Smith, E. J., Blomberg, L. A., Modise, T., Tafer, Hakim, Schmidt, C. J., William S Payne, Dong, Jennifer J., Florea Liliana, Vilella, A. J., Notredame, C., Lee, M. K., Smith, J., Kathryn Beal, Jiang, A., Bouffard, Pascal, Geo Pertea, Mi-Kyung Lee, Mane, S., Roberts, Richard J., Delany, M. E., Jerry B. Dodgson, Schmidt, Carl J., Pertea, Geo, Searle Stephen M. J., Williams, K. P., Frederickson Karin M., Beal, K., Tim T Harkins, Lee, T., Langenberger, David, Searle, S. M. J., Ruffier, M., Puiu, D., Dalloul, R. A., Van Tassell, C. P., Schatz, M. C., Julie A Long, Jennifer J Dong, Raineri, E., Modise Thero, Long Julie A., Reed, Kent M., De, Supriyo, Oswald Crasta, Zimin, Aleksey V., Folkerts, O., Zhang, Y., Schroeder Steven, Roger A Coulombe, Hoffmann Steve, Crasta, Oswald, McElroy, Audrey P., Tu, Zhijian Jake, Florea, L., Magali Ruffier, de, J. P., Curtis P. Van Tassell, Williams Kelly P., William S. Payne, Megens, H. J., Zhang, X., Bouffard, P., James A Yorke, Kaiser, Pete, Daniela Puiu, Stephen M. J. Searle, Modise, T., Notredame Cédric, Groenen, M. A. M., Hoffmann, Steve, Notredame, C��dric, Ruffier Magali, Taeheon Lee, Guillaume Marcais, Evans Clive, Le Ann Blomberg, Qioa, Dan, Herrero Javier, Zhang Liqing, Crooijmans, R. P., Kim, S., Evans, C., Prickett, Dennis, Groenen, M. A., Cooper, K., Tu, Z. J., Dalloul, R.A., De Supriyo, Kaiser, P., Schmidt, C. J., Van Tassell Curtis P., Tafer, H., Megens, Hendrik-Jan, Mane, Shrinivasrao P., Tafer, H., Marcais, G., Xiaojun Zhang, Crasta, O., Kyu-Won Kim, Dodgson Jerry B., Aleksey V. Zimin, Reed, K. M., Steve Hoffmann, Tu, Zhijian (Jake), Dalloul, Rami A., Ann Blomberg Le, Hoffmann, S., Zhang, Yang, David W Burt, Kent M. Reed, Pieter de Jong, Aslam, Luqman, Marz, M., Groenen, Martien A. M., Michael C Schatz, Zhijian Jake Tu, Burt David W., Pascal Bouffard, Pertea Geo, Richard P M A Crooijmans, Audrey P. McElroy, David W. Burt, Sonstegard, T. S., Marcais, G., Hakim Tafer, Smith, J., Zhang, H. B., Ruffier, Magali, Mikhail Nefedov, Albert J Vilella, Megens Hendrik-Jan, Clive Evans, Hendrik-Jan Megens, Kaiser Pete, Dennis Prickett, Puiu Daniela, Dan Qioa, Schroeder, S., Zhang, Hong-Bin, Zhang, Xiaojun, Audrey P McElroy, Zimin Aleksey V., Vilella, Albert J., Groenen, M. A. M., Martien A M Groenen, Coulombe, R. A., Supriyo De, Scheuring, C., Qioa, D., Van, T. C. P., Nefedov, M., Kim, K.-W., de Jong Pieter, McElroy, A. P., Folkerts, Otto, Yorke James A., Harkins, Tim T., Rami A. Dalloul, Zhijian (Jake) Tu, Lee Taeheon, Crooijmans, R.P.M.A., Searle, S. M., Megens, H. J., Edward J. Smith, Paton Ian R., Salzberg, S. L., Aleksey V Zimin, Cooper Kristal, Ian R. Paton, Emanuele Raineri, Langenberger David, Tu Zhijian (Jake), Long, J. A., Qioa, D., Coulombe, R. A., Pete Kaiser, Aslam Luqman, Mane, S., Delany, M. E., Schatz, M. C., Sonstegard Tad S., Marz, Manja, Payne, William S., Carl J Schmidt, Andrew Jiang, Tu, Z., James A. Yorke, Long, J.A., Kelly P Williams, Lee, T., Edward J Smith, Notredame, Cédric, Stadler, P. F., Aslam, L., Prickett Dennis, Zimin, A. V., Herrero, J., Searle, S. M. J., Burt, D. W., Luqman Aslam, Crasta, O., Langenberger, D., Kaiser, P., Stadler, P. F., Van Tassell, Curtis P., Schmidt Carl J., Sonstegard, Tad S., Marz Manja, Lee, M. K., Puiu, Daniela, Marcais Guillaume, Crooijmans Richard P. M. A., Blomberg, Le Ann, Groenen Martien A. M., de Jong, P., Ruffier, M., Tad S. Sonstegard, Dalloul, R. A., Jiang Andrew, Frederickson, K. M., Florea, Liliana, Aslam, M.L., Smith Edward J., de Jong, Pieter, Cédric Notredame, Kim, K. W., Searle, Stephen M. J., Smith, Jacqueline, Harkins, T. T., Smith, Edward J., Karin M Frederickson, Chantel Scheuring, Marcais, Guillaume, Dalloul Rami A., Curtis P Van Tassell, Kim, Kyu-Won, Kim, S., Mary E Delany, Hong-Bin Zhang, Michael C. Schatz, Scheuring, Chantel, Kim Kyu-Won, Jiang, Andrew, Payne, W. S., Folkerts Otto, Zhang, H. B., Zimin, A. V., Schroeder, Steven, Yorke, J. A., Megens, H.J.W.C., Heebal Kim, Payne, W. S., Ann Blomberg, Le, Beal, K., Smith, Jacqueline; id_orcid, Puiu, D., Reed, K. M., Crooijmans, R. P. M. A., Qioa Dan, Notredame, C., Pertea, G., Stephen M J Searle, Zhang Xiaojun, Prickett, D., Flicek, P., Salzberg, S. L., Karin M. Frederickson, Florea, L., Coulombe, Roger A., Smith, E. J., Delany Mary E., Scheuring Chantel, Sungwon Kim, Salzberg Steven L., Aslam, L., Jerry B Dodgson, Yang Zhang, Yorke, James A., Raineri, Emanuele, Paton, I. R., Bouffard, P., Tafer Hakim, Cooper, K., Dong, J. J., Nefedov, Mikhail, Kim Heebal, Cooper, Kristal, Roger A. Coulombe, Tim T. Harkins, Tad S Sonstegard, De, S., Nefedov, M., Herrero, Javier, Blomberg, L. A., Lee, M.-K., Mary E. Delany, Raineri, E., Zhang, L., Hoffmann, S., De, S., Peter F Stadler, Kim, Sungwon, Zhang, X., Thero Modise, Beal, Kathryn, Sonstegard, T. S., Richard P. M. A. Crooijmans, Prickett, D., Steven Schroeder, Payne William S., Jennifer J. Dong, Groenen, M., Ann Blomberg, L., Lee Mi-Kyung, Zhang, Y., Flicek, P., Zimin, A.V., Dong Jennifer J., Schatz, Michael C., Coulombe Roger A., Peter F. Stadler, Flicek Paul, Javier Herrero, Paton, Ian R., Herrero, J., Ian R Paton, Dodgson, Jerry B., Steven L Salzberg, Shrinivasrao Mane, Stadler, Peter F., Pertea, G., Reed Kent M. +405 morecore +1 more sourceHaplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine
Advanced Science, EarlyView.This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...Yanling Peng, Lianzhu Zhou, Xinyue Fang, Ruoyan Zhao, Qi Xu, Mengrui Du, Ting Hou, Guizhou Huang, Yingchun Zhang, Sheng Yan, Ruo Yang, Zhongxin Jin, Yang Dong, Yanshuai Xu, Hua Xiao, Xiaodong Xu, Yi Liao, Xiping Wang, Yongfeng Zhou +18 morewiley +1 more sourceDNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics
Advanced Science, EarlyView.This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen +12 morewiley +1 more source
