Results 11 to 20 of about 1,436,145 (318)
Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in nearly physiologic ratios and concentrations. Group O whole blood that contains low titers of anti-A and anti-B antibodies (low titer group O whole blood) can be safely ...
Cap, Andrew P. +24 more
openaire +3 more sources
In vitro comparison of cold‐stored whole blood and reconstituted whole blood
AbstractBackground and ObjectivesCold‐stored whole blood (CSWB) is increasingly used in damage control resuscitation. Haemostatic function of CSWB seems superior to that of reconstituted whole blood, and it is sufficiently preserved for 14–21 days. To provide evidence for a yet insufficiently studied aspect of prehospital CSWB use, we compared in vitro
Sanna Susila +4 more
openaire +3 more sources
Whole blood optical biosensor [PDF]
The future of rapid point-of-care diagnostics depends on the development of cheap, noncomplex, and easily integrated systems to analyze biological samples directly from the patient (e.g. blood, urine, and saliva). A key concern in diagnostic biosensing is signal differentiation between non-specifically bound material and the specific capture of target ...
Lisa M. Bonanno, Lisa A. DeLouise
openalex +3 more sources
Qualitative Evaluation of Platelet Concentrates Prepared with Different Methods [PDF]
Introduction: One of the most important responsibility of Blood Bank is to ensure uninterrupted supply of quality blood products, namely Platelet Concentrate (PC), which are in high demand particularly during pandemic. In India, PCs are of three types
Varshashree, Subhashis das, K Prabhakar
doaj +1 more source
Improved translation of stability for conjugated antibodies using an in vitro whole blood assay
For antibody-drug conjugates to be efficacious and safe, they must be stable in circulation to carry the payload to the site of the targeted cell. Several components of a drug-conjugated antibody are known to influence stability: 1) the site of drug ...
Aimee Fourie-O’Donohue +15 more
doaj +1 more source
Association of NAD+ levels with metabolic disease in a community-based study
BackgroundNicotinamide adenine dinucleotide (NAD+) is a coenzyme and plays a crucial role in several metabolic processes. This study explored the association of nicotinamide adenine dinucleotide (NAD+) levels with metabolic disease (MD) in adults ...
Yuhe Liu +11 more
doaj +1 more source
Stability of proinsulin in whole blood [PDF]
Proinsulin, the precursor for insulin, is secreted in higher concentrations when β-cells are under stress and previous studies have shown that elevated proinsulin could be used as a marker for individuals in a pre-diabetic state. The aim of this study was to assess the stability of proinsulin across a wide concentration range (3-882 and 2-187pmol/L ...
Dominic J, Bright +3 more
openaire +3 more sources
Rapid antibiotic susceptibility tests, performed directly on whole blood samples, will offer great clinical advantages. This issue is of considerable importance when it comes to bioterror pathogens where prompt antibiotic treatment should be offered to ...
Shahar Rotem +5 more
doaj +1 more source
Study of reasons for discarding whole blood and its components in a blood bank in a rural tertiary care teaching hospital in Maharashtra [PDF]
Introduction: Each unit of blood is valuable; thus, it must be used as efficiently as possible with the least amount of waste. Supply of blood in an emergency requires stringent storage conditions with quality checked and should be available at the time ...
Syeda Lubna +3 more
doaj +1 more source
Large-scale genetic epidemiological studies require high-quality analysis of samples such as blood or saliva from multiple patients, which is challenging at the point of care.
Kiara Lee, Anubhav Tripathi
doaj +1 more source

