Results 11 to 20 of about 77,543 (273)

Integration of Transcriptome and Metabolome Provides Unique Insights to Pathways Associated With Obese Breast Cancer Patients

open access: yesFrontiers in Oncology, 2020
Information regarding transcriptome and metabolome has significantly contributed to identifying potential therapeutic targets for the management of a variety of cancers.
Mohammed A. Hassan   +18 more
doaj   +1 more source

A Flow Cytometry-Based Whole Blood Natural Killer Cell Cytotoxicity Assay Using Overnight Cytokine Activation

open access: yesFrontiers in Immunology, 2020
Background: Measurement of natural killer (NK) cell function has important clinical utility in several diseases. Although the flow cytometry (FC)-based 4-h NK cytotoxicity assay using peripheral blood mononuclear cells (PBMCs) in the clinical laboratory ...
Jinho Kim   +12 more
doaj   +1 more source

Stability of proinsulin in whole blood [PDF]

open access: yesClinical Biochemistry, 2018
Proinsulin, the precursor for insulin, is secreted in higher concentrations when β-cells are under stress and previous studies have shown that elevated proinsulin could be used as a marker for individuals in a pre-diabetic state. The aim of this study was to assess the stability of proinsulin across a wide concentration range (3-882 and 2-187pmol/L ...
Stephen D. Luzio   +3 more
openaire   +4 more sources

Comparative evaluation of platelet count in whole blood and injectable platelet-rich fibrin

open access: yesDentistry and Medical Research, 2021
Background: Platelets are formed from megakaryocytes and platelets are present in the circulation for 5–7 days. Platelets are essential in hemostasis, vascular integrity, angiogenesis, inflammation, innate immunity, and wound healing.
Aarati Nayak   +4 more
doaj   +1 more source

Immersed boundary simulations of cell-cell interactions in whole blood [PDF]

open access: yes, 2021
We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv   +1 more source

Trace element status of highly productive cows in different physiological conditions under increased technogenic load

open access: yesRUDN Journal of Agronomy and Animal Industries, 2022
Microelements play a vital role in the maintenance and intensification of metabolic and regulatory processes in the body of animals. For a more complete study of provision of body of highly productive animals with microelements and diagnosis of metabolic
Oleg S. Drozhzhin, Valeriy V. Shipilov
doaj   +1 more source

DNA Methylation Profiles in Whole Blood of Huntington's Disease Patients

open access: yesFrontiers in Neurology, 2018
Epigenetic mechanisms, especially DNA methylation, are suggested to play a role in the age-of-onset in Huntington's disease (HD) based on studies on patient brains, and cellular and animal models. Methylation is tissue-specific and it is not clear how HD
Maja Zadel   +4 more
doaj   +1 more source

A nested case-control study on zinc levels in maternal whole blood and fetal cord blood and risk of congenital heart disease in offspring

open access: yes环境与职业医学, 2022
BackgroundZinc is a trace element essential for normal fetal heart development, and excess zinc can be toxic. The relationship between maternal and fetal zinc levels and the development of congenital heart disease (CHD) in the offspring is unclear ...
Qian LIU   +6 more
doaj   +1 more source

Study of “Discard Rate” of Whole Human Blood: Useful Blood Center Quality Indicator

open access: yesJournal of the Scientific Society, 2018
Background: Blood is a valuable, life-saving material which should not be discarded or wasted to have the required blood supply to the patients. Aims and Objectives: The aim of the present study is to find out the major causes of blood discard from the ...
Gopeswar Mukherjee   +3 more
doaj   +1 more source

The Stability of Analytes of Ionized Magnesium Concentration and Its Reference Range in Healthy Volunteers

open access: yesBiomedicines, 2023
This study aimed to determine the stability of refrigerated analytes of iMg concentration at different time intervals and to establish iMg reference range in a cohort of healthy Omani volunteers (≥18 years).
Juhaina Salim Al-Maqbali   +5 more
doaj   +1 more source

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