Results 21 to 30 of about 5,584,779 (298)

Mistimed sleep and waking activity in humans disrupts glucocorticoid signalling transcripts and SP1, but not plasma cortisol rhythms

Frontiers in Physiology, 2022
Cortisol is a robust circadian signal that synchronises peripheral circadian clocks with the central clock in the suprachiasmatic nucleus via glucocorticoid receptors that regulate peripheral gene expression.
Simon N. Archer, Carla S. Möller-Levet, Emma E. Laing, Derk-Jan Dijk, Derk-Jan Dijk   +4 more
doaj   +1 more source

Diagnostic Value and Clinical Application of mNGS for Post-Liver Transplantation Infection: A Cross-Sectional Study With Case Reports

Frontiers in Microbiology, 2022
Liver transplantation is widely acknowledged as the only effective treatment for end-stage liver disease, and infection is reportedly an important cause of postoperative death.
Dong Zhao, Liping Guo, Dongli Lian, Yuchen Gu, Xu Yan, Hongxing Hu, Jing Yuan   +6 more
doaj   +1 more source

Whole Blood Holding Time Prior to Plasma Processing Alters microRNA Expression Profile

Frontiers in Genetics, 2022
MicroRNAs (miRNAs) can exhibit aberrant expression under different physiological and pathological conditions. Therefore, differentially expressed circulating miRNAs have been a focus of biomarker discovery research. However, the use of circulating miRNAs
Sung Hye Kim, Sung Hye Kim, David A. MacIntyre, David A. MacIntyre, Lynne Sykes, Lynne Sykes, Maria Arianoglou, Maria Arianoglou, Phillip R. Bennett, Phillip R. Bennett, Vasso Terzidou, Vasso Terzidou, Vasso Terzidou   +12 more
doaj   +1 more source

Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers

Pharmaceuticals, 2020
Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(−)-mephedrone.
Joanna Czerwinska, Mark C. Parkin, Agostino Cilibrizzi, Claire George, Andrew T. Kicman, Paul I. Dargan, Vincenzo Abbate   +6 more
doaj   +1 more source

Intravenous Iron Sucrose versus Packed Cell Volume for Treatment of Severe Iron Deficiency Anaemia in Pregnancy: A Randomization Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Severe Iron Deficiency Anaemia (IDA) in pregnancy is usually treated with whole blood or Packed Cell Volume (PCV) transfusion to maintain feto-placental perfusion and replete the haemodynamic mechanisms before delivery.
Girija Wagh
doaj   +1 more source

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S., Chaudhry, M.A., Muriithi, E.W., Belcher, P.R.   +3 more
core   +8 more sources

An Anti-Nucleocapsid Antigen Sars-Cov-2 Total Antibody Assay Finds Comparable Results in Edta-Anticoagulated Whole Blood Obtained from Capillary and Venous Blood Sampling

Data, 2020
Although SARS-CoV-2 antibody assays have been found to provide valid results in EDTA-anticoagulated whole blood, so far, they have not demonstrated that antibody levels in whole blood originating from capillary blood samples are comparable to antibody ...
Martin Risch, Marc Kovac, Corina Risch, Dorothea Hillmann, Michael Ritzler, Nadia Wohlwend, Thomas Lung, Michael Allmann, Christoph Seger, Lorenz Risch   +9 more
doaj   +1 more source

The quality of stored umbilical cord and adult-donated whole blood in Mombasa, Kenya. [PDF]

, 2009
BACKGROUND: In sub-Saharan Africa umbilical cord blood may be a useful source of blood for transfusion. Before clinical trials, evidence is needed that cord blood donations, which vary greatly in volume, can be collected and stored into a fixed volume of
Hassall, O, Maitland, Kathryn, Robert Mwakesi, Douglas Denje, Hassall, Oliver, Thitiri, J, Mandaliya, K, Kathryn Maitland, Fegan, Gregory, Denje, Douglas, Bates, I, Bates, Imelda, Imelda Bates, Maitland, K, Oliver Hassall, Bates, Imelda; id_orcid, Wambua, Kongo, Pole, Lewa, Wambua, K, Mandaliya, Kishor, Mwakesi, Robert, Mwakesi, R, Lewa Pole, Fegan, G, Kongo Wambua, Kishor Mandaliya, Denje, D, Thitiri, Johnstone, Johnstone Thitiri, Pole, L, Gregory Fegan, Greg Fegan   +31 more
core   +1 more source

Clinical Validation of a Volumetric Absorptive Micro-Sampling Device for Pharmacokinetic Studies With Tranexamic Acid

Frontiers in Pharmacology, 2021
We assessed the accuracy of tranexamic acid (TXA) concentrations measured in capillary whole blood using volumetric absorptive micro-sampling (VAMS) devices.
Stanislas Grassin-Delyle, Stanislas Grassin-Delyle, Elodie Lamy, Michaela Semeraro, Iléana Runge, Jean-Marc Treluyer, Jean-Marc Treluyer, Raoul Mansukhani, Monica Arribas, Ian Roberts, Haleema Shakur-Still   +10 more
doaj   +1 more source

Driving Under the Influence of Drugs: A Single Parallel Monitoring-Based Quantification Approach on Whole Blood

Frontiers in Chemistry, 2020
Driving under the influence of psychoactive substances is a major cause of motor vehicle crashes. The identification and quantification of substances most frequently involved in impaired-driving cases in a single analytic procedure could be an important ...
Timothée Joye, Timothée Joye, Katell Rocher, Julien Déglon, Jonathan Sidibé, Bernard Favrat, Bernard Favrat, Marc Augsburger, Aurélien Thomas, Aurélien Thomas   +9 more
doaj   +1 more source