Results 11 to 20 of about 1,479,555 (266)

Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers

Pharmaceuticals, 2020
Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(−)-mephedrone.
Joanna Czerwinska, Mark C. Parkin, Agostino Cilibrizzi, Claire George, Andrew T. Kicman, Paul I. Dargan, Vincenzo Abbate   +6 more
doaj   +1 more source

Intravenous Iron Sucrose versus Packed Cell Volume for Treatment of Severe Iron Deficiency Anaemia in Pregnancy: A Randomization Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Severe Iron Deficiency Anaemia (IDA) in pregnancy is usually treated with whole blood or Packed Cell Volume (PCV) transfusion to maintain feto-placental perfusion and replete the haemodynamic mechanisms before delivery.
Girija Wagh
doaj   +1 more source

An Anti-Nucleocapsid Antigen Sars-Cov-2 Total Antibody Assay Finds Comparable Results in Edta-Anticoagulated Whole Blood Obtained from Capillary and Venous Blood Sampling

Data, 2020
Although SARS-CoV-2 antibody assays have been found to provide valid results in EDTA-anticoagulated whole blood, so far, they have not demonstrated that antibody levels in whole blood originating from capillary blood samples are comparable to antibody ...
Martin Risch, Marc Kovac, Corina Risch, Dorothea Hillmann, Michael Ritzler, Nadia Wohlwend, Thomas Lung, Michael Allmann, Christoph Seger, Lorenz Risch   +9 more
doaj   +1 more source

Stability of proinsulin in whole blood [PDF]

Clinical Biochemistry, 2018
Proinsulin, the precursor for insulin, is secreted in higher concentrations when β-cells are under stress and previous studies have shown that elevated proinsulin could be used as a marker for individuals in a pre-diabetic state. The aim of this study was to assess the stability of proinsulin across a wide concentration range (3-882 and 2-187pmol/L ...
Dominic J, Bright, Gareth J, Dunseath, Rajesh, Peter, Stephen, Luzio   +3 more
openaire   +4 more sources

Clinical Validation of a Volumetric Absorptive Micro-Sampling Device for Pharmacokinetic Studies With Tranexamic Acid

Frontiers in Pharmacology, 2021
We assessed the accuracy of tranexamic acid (TXA) concentrations measured in capillary whole blood using volumetric absorptive micro-sampling (VAMS) devices.
Stanislas Grassin-Delyle, Stanislas Grassin-Delyle, Elodie Lamy, Michaela Semeraro, Iléana Runge, Jean-Marc Treluyer, Jean-Marc Treluyer, Raoul Mansukhani, Monica Arribas, Ian Roberts, Haleema Shakur-Still   +10 more
doaj   +1 more source

Driving Under the Influence of Drugs: A Single Parallel Monitoring-Based Quantification Approach on Whole Blood

Frontiers in Chemistry, 2020
Driving under the influence of psychoactive substances is a major cause of motor vehicle crashes. The identification and quantification of substances most frequently involved in impaired-driving cases in a single analytic procedure could be an important ...
Timothée Joye, Timothée Joye, Katell Rocher, Julien Déglon, Jonathan Sidibé, Bernard Favrat, Bernard Favrat, Marc Augsburger, Aurélien Thomas, Aurélien Thomas   +9 more
doaj   +1 more source

Alinity m, a Random-Access System, for Hepatitis B Virus DNA Quantification in Plasma and Whole Blood Collected on Dried Blood Spots

mSphere, 2022
The International Liver Association recommends the use of accurate and sensitive molecular methods for determination of hepatitis B virus (HBV) DNA levels in plasma or serum of chronic HBsAg carriers. The level of HBV replication represents the strongest
Valérie Ortonne, Quentin Lucas, Olivia Garrigou, Alexandre Soulier, Dominique Challine, Jean-Michel Pawlotsky, Vincent Leroy, Stéphane Chevaliez   +7 more
doaj   +1 more source

Blood pressure and expression of microRNAs in whole blood.

PLoS ONE, 2017
BackgroundBlood pressure (BP) is a complex, multifactorial clinical outcome driven by genetic susceptibility, behavioral choices, and environmental factors.
Zhou Zhang, Brian Thomas Joyce, Jacob K Kresovich, Yinan Zheng, Jia Zhong, Ruchi Patel, Wei Zhang, Lei Liu, Chang Dou, John P McCracken, Anaité Díaz, Valeria Motta, Marco Sanchez-Guerra, Shurui Bian, Pier Alberto Bertazzi, Joel Schwartz, Andrea A Baccarelli, Sheng Wang, Lifang Hou   +18 more
doaj   +1 more source

High-Efficiency Plasma Separator Based on Immunocapture and Filtration

Micromachines, 2020
The shortcomings of standard plasma-separation methods limit the point-of-care application of microfluidics in clinical facilities and at the patient’s bedside.
Xiaosong Su, Jianzhong Zhang, Dongxu Zhang, Yingbin Wang, Mengyuan Chen, Zhenyu Weng, Jin Wang, Juntian Zeng, Ya Zhang, Shiyin Zhang, Shengxiang Ge, Jun Zhang, Ningshao Xia   +12 more
doaj   +1 more source

Infusion therapy as an important element of anesthetic strategy for the wounded with hemorrhagic shock

Медицина неотложных состояний, 2022
Hemorrhagic shock remains the main cause of death of the wounded in all wars and military conflicts. A key aspect in modern anesthetic strategy for the wounded with hemorrhagic shock is the strategy of a balanced infusion therapy.
O.V. Raboshchuk, G.P. Khytriy, V.M. Moshkivskyi, M.A. Khodakivskyi   +3 more
doaj   +1 more source