Results 21 to 30 of about 3,071,871 (357)

HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia [PDF]

, 2017
Preeclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify dysregulated genes in maternal whole blood samples which may be ...
Akehurst, Christine, Carty, David M., Delles, Christian, Freeman, Dilys J., McBride, Martin W., McClure, John D., Robinson, Scott W., Sharafetdinova, Lilya, Small, Heather Y.   +8 more
core   +1 more source

A clinically validated human capillary blood transcriptome test for global systems biology studies

BioTechniques, 2020
To prevent and treat chronic diseases, including cancer, a global application of systems biology is needed. We report here a whole blood transcriptome test that needs only 50 μl of capillary (fingerprick) blood.
Ryan Toma, Nathan Duval, Benjamin Pelle, Matthew M Parks, Vishakh Gopu, Pedro J Torres, Francine R Camacho, Nan Shen, Subha Krishnan, Andrew Hatch, Hal Tily, Ally Perlina, Guruduth Banavar, Momchilo Vuyisich   +13 more
doaj   +1 more source

In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model

Frontiers in Immunology, 2023
Iron oxide nanoparticles (IONPs) are widely used in diagnostic and therapeutic settings. Upon systemic administration, however, they are rapidly recognized by components of innate immunity, which limit their therapeutic capacity and can potentially lead ...
Alexandra Gerogianni, Alexandra Gerogianni, Melissa Bal, Melissa Bal, Camilla Mohlin, Camilla Mohlin, Trent M. Woodruff, John D. Lambris, Tom E. Mollnes, Tom E. Mollnes, Tom E. Mollnes, Dick J. Sjöström, Dick J. Sjöström, Per H. Nilsson, Per H. Nilsson, Per H. Nilsson   +15 more
doaj   +1 more source

Spaceflight modulates gene expression in the whole blood of astronauts [PDF]

, 2016
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to disease, including infectious diseases.
Barrila, Jennifer, Crabbé, Aurélie, LeBlanc, Carly, Mehta, Satish K, Nickerson, Cheryl A, Ott, C Mark, Pierson, Duane L, Stafford, Phillip   +7 more
core   +2 more sources

Comparison of the frequency and phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cells between the site of disease and blood in pericardial tuberculosis

Frontiers in Immunology, 2022
Studies of the immune response at the site of disease in extra-pulmonary tuberculosis (EPTB) disease are scarce. In this study, we compared the cellular profile of Mycobacterium tuberculosis (Mtb)-specific T cells in pericardial fluid and peripheral ...
Elsa Du Bruyn, Sheena Ruzive, Patrick Howlett, Maddalena. Cerrone, Maddalena. Cerrone, Maddalena. Cerrone, Ashley J. Jacobs, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Alessandro Sette, Alan Sher, Katrin D. Mayer-Barber, Daniel L. Barber, Bongani Mayosi, Bongani Mayosi, Mpiko Ntsekhe, Mpiko Ntsekhe, Mpiko Ntsekhe, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Catherine Riou, Catherine Riou   +23 more
doaj   +1 more source

Impact of Active Recovery and Whole-Body Electromyostimulation on Blood-Flow and Blood Lactate Removal in Healthy People [PDF]

, 2020
This study aimed to determine whether an active recovery with added whole-body electromyostimulation (WB-EMS) can increase blood flow and lead to blood lactate removal after intense exercise.
Babault, Barnett, Bieuzen, Borne, Currier, de la Camara Serrano, Dupuy, Erten, Griffin, Hopkins, Kaplan, Kastner, Kemmler, Kemmler, Kemmler, Kuipers, Lattier, Malone, Martin, Menendez, Neric, Nosaka, Pano-Rodriguez, Sheriff, Signorile, Toubekis, Tucker, Vanderthommen, Williams   +28 more
core   +1 more source

Self-powered microfluidic chips for multiplexed protein assays from whole blood [PDF]

, 2009
We report herein on a self-powered, self-contained microfluidic-based chip designed to separate plasma from whole blood, and then execute an assay of a multiplexed panel of plasma biomarker proteins.
Heath, James R., Qin, Lidong, Shi, Qihui, Vermesh, Ophir   +3 more
core   +2 more sources

Elevating microRNA-122 in blood improves outcomes after temporary middle cerebral artery occlusion in rats. [PDF]

, 2016
Because our recent studies have demonstrated that miR-122 decreased in whole blood of patients and in whole blood of rats following ischemic stroke, we tested whether elevating blood miR-122 would improve stroke outcomes in rats.
Ander, Bradley P, Cox, Christopher, Dykstra-Aiello, Cheryl, Hull, Heather, Jickling, Glen C, Liu, Da Zhi, Sharp, Frank R, Shroff, Natasha, Stamova, Boryana, Zhan, Xinhua   +9 more
core   +2 more sources

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source

Quality of DNA extracted from formalin-fixed, paraffin-embedded canine tissues. [PDF]

, 2020
Veterinary pathology tissue banks are valuable resources for genetic studies. However, limited data exist as to whether quality DNA can be extracted from these tissues for use in canine genotyping studies.
Bannasch, Danika L, Dear, Jonathan D, Sykes, Jane E   +2 more
core   +1 more source