Results 51 to 60 of about 3,112,739 (313)

Parylene membrane slot filter for the capture, analysis and culture of viable circulating tumor cells [PDF]

open access: yes, 2010
This paper presents a method of capturing viable circulating tumor cells (CTC) from human whole blood using constant-pressure-driven filtration through a specially designed parylene-C membrane “slot” filter. More than 90% viable cancer cells could be
Goldkorn, Amir   +4 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Effects of pre-storage leukoreduction on erythrocyte concentrates and performance of newer generation leuko-filters at a tertiary care oncology hospital in Western India

open access: yesAfrican Journal of Laboratory Medicine
Background: Leukoreduction is a post-processing technique that reduces residual leukocytes in cellular blood components. Previous studies have evaluated these parameters mainly among older generation leuko-filters.
Deep Madkaiker   +3 more
doaj   +1 more source

Impact of the COVID-19 Pandemic on Blood Supply

open access: yesPhilippine Journal of Pathology, 2023
Objective. The study aimed to determine the impact of the COVID-19 pandemic on local blood supply management in the Davao Region, Philippines from 2019 to 2021 through the analysis of trends in blood supply in Davao Region, Philippines.
Johnmerson Yap   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Biomarker discovery for non-invasive diagnosis of inflammatory bowel disease using blood transcriptomics

open access: yesFrontiers in Immunology
IntroductionColonoscopy remains the gold standard for diagnosing inflammatory bowel disease (IBD) even though it is an invasive and costly procedure.
Mohammad Hossein Derakhshan Nazari   +3 more
doaj   +1 more source

Whole blood transfusion in small animals: indications and effects

open access: yesAnais da Academia Brasileira de Ciências, 2011
Transfusion therapy is a major resource that can improve the patient's capability to overcome the underlying disease. However, the effects of whole blood infusion, and how they affect the patient's outcome, are not yet clear.
Luís F Godinho-Cunha   +2 more
doaj   +1 more source

Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation [PDF]

open access: yes, 1985
The blood coagulation system of 66 consecutive patients undergoing consecutive liver transplantations was monitored by thrombelastograph and analytic coagulation profile.
Bontempo, FA   +7 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Estimation of cell-type composition including T and B cell subtypes for whole blood methylation microarray data

open access: yesFrontiers in Genetics, 2016
DNA methylation levels vary markedly by cell-type makeup of a sample. Understanding these differences and estimating the cell-type makeup of a sample is an important aspect of studying DNA methylation.
Lindsay L Waite   +10 more
doaj   +1 more source

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