Results 141 to 150 of about 3,996,555 (297)

Whole-Brain Radiotherapy [PDF]

, 2020
openaire   +1 more source

Quality of Life in Children Who Are Deaf or Hard‐of‐Hearing and Their Families—A Scoping Review

The Laryngoscope, EarlyView.
This scoping review examines how quality of life is conceptualized and studied in young deaf and hard‐of‐hearing children and their families. The findings reveal inconsistent use of the term Quality of life, limiting cross‐study comparisons. Additionally, research is focused on children with cochlear implants while other groups remain underrepresented.
Nina Jakhelln Laugen, Evelien Dirks, Kerttu Huttunen   +2 more
wiley   +1 more source

The Influences of Whole Brain Radiotherapy on Social Cognition and Association with Hippocampal and Frontal Dosimetry

, 2015
The influence of brain radiotherapy on neurocognition is a major concern. Social cognition is a mental process in the meaning of social interaction and the recognition of facial emotion is a domain of social cognition.
Yassa, Ahmet, Yuksek, Erhan, Eroz, Seda, Akturk, Dilara, Emul, Murat, Akcam, Funda Engin, Zakirov, Fagan   +6 more
core   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Brain Radiotherapy Combined with Targeted Therapy for HER2-Positive Breast Cancer Patients with Brain Metastases [PDF]

Lifeng Tang,1,2 Wei Zhang,3 Long Chen2 1Department of Oncology, Liuzhou People’s Hospital, Liuzhou, Guangxi, 545006, People’s Republic of China; 2Department of Radiotherapy, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People’s ...
Zhang W, Tang L, Chen L
core  

Patient iPSC‐derived astrocytes reveal impaired homeostasis and reactive‐like features in propionic acidemia

The Journal of Pathology, EarlyView.
Abstract Propionic acidemia (PA) is a neurometabolic disorder caused by propionyl‐CoA carboxylase deficiency with frequent neurological involvement, yet cell‐type‐specific mechanisms remain poorly defined. We established human induced pluripotent stem cell (iPSC)‐derived astrocytes (iAs) from patients harboring PCCA or PCCB mutations and investigated ...
Irene González‐Garnacho, Mar Álvarez, Francisco Zafra, Pilar Rodríguez‐Pombo, Lourdes R Desviat, Eva Richard   +5 more
wiley   +1 more source

Preclinical validation of a clinical prototype of intraoperative electron FLASH radiotherapy equipment: key evidence for a new radiotherapy paradigm

Radiation Oncology
Background and purpose This study aimed to evaluate whether the clinical prototype of intraoperative electron FLASH radiotherapy (CPIO-EFLASH), with a source-surface distance (SSD) of 50 cm, could achieve ultra-high dose rates, effectively control tumors,
Xiaofei Hao, Huan Du, Binwei Lin, Yang Xia, Mingming Tang, Wei Wu, Decai Wang, Yihan Zhu, Yu Zhang, Jianxin Wang, Yiwei Yang, Dai Wu, Xiaobo Du   +12 more
doaj   +1 more source

Stem cell–mediated neuroplasticity and psychological recovery in cancer survivors: Mechanisms, evidence, and translational challenges

Precision Medical Sciences, EarlyView.
Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley   +1 more source

A comprehensive Sustainable Development Goal‐guided framework for advancing survivorship, rehabilitation, and quality of life in breast cancer patients

Precision Medical Sciences, EarlyView.
This article presents an Sustainable Development Goal‐aligned framework integrating survivorship care, rehabilitation, and quality‐of‐life strategies for breast cancer patients, emphasizing equity, gender responsiveness, and health system strengthening. It highlights multidisciplinary, patient‐centered interventions and global partnerships as essential
Emmanuel Ifeanyi Obeagu
wiley   +1 more source