Results 151 to 160 of about 3,996,555 (297)
Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use
The Prostate, EarlyView.ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley +1 more source
Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists
SmartBot, EarlyView.Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu +12 more
wiley +1 more source
Small, EarlyView.A luminescent PEI/Cy5‐citrate‐functionalized carbonated apatite nanoplatform combines biocompatibility, plasmid delivery, and Cy5‐based traceability. The system enables effective in vitro gene delivery while preserving cell viability and allows real‐time in vivo fluorescence tracking of the nanocarrier.
Laura Garrido Martín +5 more
wiley +1 more source
Advances in research on layered double hydroxides for biomedical applications
Smart Molecules, EarlyView.Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Smart Molecules, EarlyView.MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag +6 more
wiley +1 more source
A Multi‐Sequence Adversarial Fusion U‐Net for Brain Tumor Image Segmentation
IEEJ Transactions on Electrical and Electronic Engineering, EarlyView.In the field of brain tumor image segmentation, in order to avoid the impact of insufficient number of training samples, the method of fusing multi‐modal MRI information before segmentation is widely used. However, when fusing different modal features, existing methods only add fixed weights to the features of each modality, resulting in insufficient ...
Jie Wang, Jinglu Hu
wiley +1 more source
Review on enhancing clinical decision support system using machine learning
CAAI Transactions on Intelligence Technology, EarlyView.Abstract Clinical decision‐making is a complex patient‐centred process. For an informed clinical decision, the input data is very thorough ranging from detailed family history, environmental history, social history, health‐risk assessments, and prior relevant medical cases.
Anum Masood +4 more
wiley +1 more source
An optimized VMAT planning technique for hippocampal-sparing whole-brain radiotherapy. [PDF]
J Appl Clin Med PhysLiu B, Liu A, Williams T, Kim JH.
europepmc +1 more source
Safety and efficacy of delivering systemic treatments concomitantly with whole-brain radiotherapy: a prospective, observational, single-institution study. [PDF]
Explor Target Antitumor TherProtopapa M +10 more
europepmc +1 more source
Journal of Medical Imaging and Radiation Oncology, EarlyView.ABSTRACT Background Differentiating transition zone (TZ) prostate cancer (PCa) from benign prostatic hyperplasia (BPH) on multiparametric MRI is challenging. The comparative performance of synthetic MRI (Sy‐MRI) and apparent diffusion coefficient (ADC) for this task is unclear.
Yu Zhang +5 more
wiley +1 more source