Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer:5-year results for local control and overall survival from the TARGIT-a randomised trial [PDF]
Background: The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam radiotherapy (EBRT) for breast cancer.
Tobias, Jeffrey S. +36 more
core +1 more source
Management of brain metastases: history and the present
Brain metastases are significant causes of morbidity or mortality for patients with metastatic cancer. With the application of novel systematic therapy and improvement of overall survival, the prevalence of brain metastases is increasing. The paradigm of
Qi Liu, Xuezhi Tong, Jiangfei Wang
doaj +1 more source
Re-irradiation for Metastatic Brain Tumors with Whole-brain Radiotherapy [PDF]
To determine whether second whole-brain irradiation is beneficial for patients previously treated with whole-brain irradiation.A retrospective analysis was done for 31 patients with brain metastases who had undergone re-irradiation. Initial whole-brain irradiation was performed with 30 Gy/10 fractions for 87% of these patients.
Takeshi, Akiba +5 more
openaire +2 more sources
Hippocampal Sparing Radiotherapy in Patients with Brain Metastasis: Benefits and Risks. [PDF]
Background: Whole brain irradiation is associated with late adverse events as memory and learning decline due to damage of the hippocampus. The primary objective is to assess memory changes for patients treated with hippocampal sparing IMRT.
sherif zawawy +4 more
doaj +1 more source
Objective: to study the tolerance of radiotherapy by adding the boost and the xenon-therapy during the whole brain radiotherapy (WBRT) in patients with single brain metastasis.
M. S. Zinkovich +5 more
doaj +1 more source
Objective Previous work has demonstrated that metastases are not uniformly distributed across the brain. This study aims to determine there are low-risk brain metastasis (BM) areas that may be avoided during whole-brain radiotherapy (WBRT) to reduce ...
Binwei Lin +5 more
doaj +1 more source
Dose specification for hippocampal sparing whole brain radiotherapy (HS WBRT):Considerations from the UK HIPPO trial QA programme [PDF]
Objective: The HIPPO trial is a UK randomized Phase II trial of hippocampal sparing (HS) vs conventional wholebrain radiotherapy after surgical resection or radiosurgery in patients with favourable prognosis with 1-4 brain metastases.
Phillips, Mark +15 more
core +1 more source
Stereotactic radiosurgery and radiotherapy for resected brain metastases: current pattern of care in the Radiosurgery and Stereotactic Radiotherapy Working Group of the German Association for Radiation Oncology (DEGRO) [PDF]
PURPOSE Preoperative stereotactic radiosurgery (SRS) of brain metastases may achieve similar local control and better leptomeningeal control rates than postoperative fractionated stereotactic radiotherapy (FSRT) in patients treated with elective ...
Boström, J +28 more
core +3 more sources
Purpose Epidermal growth factor receptor (EGFR)-mutant lung cancers have a high risk of developing brain metastases (BM). Whole brain radiotherapy (WBRT), local radiotherapy, and WBRT + Boost are frequently used for treatment of BM.
Guangchuan Deng +6 more
doaj +1 more source
Metastatic brain tumor. Clinical features, diagnosis and treatment
The improvement of neuroimaging methods and introduction of the principles of microsurgery and radiosurgery involving the use of the Gamma Knife and CyberKnife systems into clinical practice have significantly changed the treatment outcomes in patients ...
Andrey V. Golanov +4 more
doaj +1 more source

