Results 11 to 20 of about 3,996,555 (297)

Whole brain radiotherapy: Consequences for personalized medicine [PDF]

Reports of Practical Oncology & Radiotherapy, 2013
Several studies focusing on brain irradiation are in progress. Reflecting updates of relevant outcomes in palliative treatment of patients suffering from brain metastases, the primary objective of these studies is the evaluation of neurocognitive function and quality of life.
Kazda, Tomáš, Pospíšil, Petr, Doleželová, Hana, Jančálek, Radim, Šlampa, Pavel   +4 more
core   +5 more sources

Concurrent whole brain radiotherapy and bortezomib for brain metastasis [PDF]

Radiation Oncology, 2013
Survival of patients with brain metastasis particularly from historically more radio-resistant malignancies remains dismal. A phase I study of concurrent bortezomib and whole brain radiotherapy was conducted to determine the tolerance and safety of this approach in patients with previously untreated brain metastasis.A phase I dose escalation study ...
Lao, CD, Friedman, J, Tsien, CI, Normolle, DP, Chapman, C, Cao, Y, Lee, O, Schipper, M, Van Poznak, C, Hamstra, D, Lawrence, T, Hayman, J, Redman, BG   +12 more
core   +6 more sources

Brain Radiotherapy and Cognition

Pediatric Neurology Briefs, 1992
Cognitive function and school achievement were studied prospectively over 3 to 4 years in 19 children treated for brain tumors with whole-brain radiotherapy at the Children’s Hospital, Philadelphia, PA.
J Gordon Millichap
doaj   +2 more sources

Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution? [PDF]

Journal of Clinical Oncology, 2018
An estimated 20% of patients with cancer will develop brain metastases. Approximately 200,000 individuals in the United States alone receive whole-brain radiotherapy (WBRT) each year to treat brain metastases. Historically, the prognosis of patients with brain metastases has been poor; however, with new therapies, this is changing.
Paul D, Brown, Manmeet S, Ahluwalia, Osaama H, Khan, Anthony L, Asher, Jeffrey S, Wefel, Vinai, Gondi   +5 more
openaire   +3 more sources

Retrospective study of hypofractionated stereotactic radiotherapy combined with whole brain radiotherapy for patients with brain metastases

Radiation Oncology, 2022
Background and purpose To evaluate the clinical outcomes of hypofractionated stereotactic radiotherapy (HFSRT) combined with whole brain radiotherapy (WBRT) in patients with brain metastases (BMs).
Xue-Yi Xie, Hong-Hua Peng, Xi Zhang, Yu-Liang Pan, Zhen Zhang, Pei-Guo Cao   +5 more
doaj   +3 more sources

Unilateral hippocampal sparing during whole brain radiotherapy for multiple brain metastases: narrative and critical review [PDF]

Frontiers in Oncology
BackgroundThe landscape of brain metastases radiotherapy is evolving, with a shift away from whole-brain radiotherapy (WBRT) toward targeted stereotactic approaches aimed at preserving neurocognitive functions and maintaining overall quality of life. For
Petr Pospisil, Petr Pospisil, Ludmila Hynkova, Ludmila Hynkova, Lucie Hnidakova, Lucie Hnidakova, Jana Maistryszinova, Jana Maistryszinova, Pavel Slampa, Pavel Slampa, Tomas Kazda, Tomas Kazda   +11 more
doaj   +2 more sources

Analysis of Prognostic Factors in NSCLC Patients with Brain Metastases 
Diagnosed by Constrast-enhanced MRI After Whole Brain Radiotherapy

Chinese Journal of Lung Cancer, 2011
Background and objective Brain metastases are a common complication of lung cancer, occurring in 20%-40% of patients. The aim of this study is to explore prognostic factors in non-small cell lung cancer (NSCLC) in patients with brain metastases diagnosed
Hui LIU, Qiongya WU, Xiaomei GONG, Xiaodong HE, Hongyu WU, Zhaoying SHENG, Dao’an ZHOU   +6 more
doaj   +2 more sources

Relapse of herpes simplex encephalitis in a patient with metastatic small cell lung cancer following scalp sparing whole brain radiotherapy

IDCases, 2019
Herpes simplex virus is the most common cause of severe and potentially fatal sporadic encephalitis worldwide. Recurrence of neurologic symptoms after resolution of the initial episode of HSV encephalitis and despite adequate treatment with intravenous ...
A. Balkhair, A. Al Wahaibi, S. Raniga, M. Al Amin, F. Ba Alawi, M. El-Tigani, S. Kumar   +6 more
doaj   +2 more sources

Improving on whole-brain radiotherapy in patients with large brain metastases: a planning study to support the AROMA clinical trial [PDF]

, 2022
PURPOSE: To develop a novel dose-escalated volumetric modulated arc therapy (VMAT) strategy for patients with single or multiple large brain metastases which can deliver a higher dose to individual lesions for better local control (LC), and to compare ...
Rozati, Hamoun, Calvez, Kerlann Le, Wang, James, Chen, Jiarong, Hill, Laurence, Pakzad-Shahabi, Lillie, Williams, Matt, Sinclair, Georges, Paddick, Ian, Kerlann Le Calvez, Georges Sinclair, Matt Williams, Hamoun Rozati, Ian Paddick, James Wang, Jiarong Chen, Laurence Hill, Lillie Pakzad-Shahabi   +17 more
core   +1 more source

A comparative study of whole brain radiotherapy with concomitant thalidomide versus whole brain radiotherapy alone in brain metastases

Journal of Cancer Research and Therapeutics, 2023
Background: Brain metastasis increases morbidity and mortality in cancer patients. This study was undertaken to compare tumor response and treatment-related toxicities in patients treated with orally administered thalidomide concomitantly with whole brain radiotherapy to whole brain radiotherapy alone in brain ...
Deiwakor, Chyrmang, Yumkhaibam S, Devi, Kishalay, Baidya, Laishram J, Singh, Daffilyne L, Nongrum, Ningthoujam D, Devi   +5 more
openaire   +2 more sources