Results 251 to 260 of about 86,818 (288)

Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences. [PDF]

open access: yesNat Ecol Evol
Yu D   +43 more
europepmc   +1 more source

Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective While RNAseq has enhanced variant interpretation in postnatal cases, its potential in the prenatal setting remains underexplored. This study investigates the utility of RNAseq in prenatal diagnostics by analyzing the expression profiles of cultured chorionic villus samples (cCVS) and amniotic fluid (cAF) samples. Methods We performed
Maria C. Vladoiu   +7 more
wiley   +1 more source

Longitudinal Single‐Cell Transcriptomic Profiling Reveals Dynamic Immune Cell Alterations During Burosumab Therapy in X‐Linked Hypophosphatemia

open access: yesPediatric Discovery, EarlyView.
This longitudinal single‐cell study reveals dynamic immune remodeling during burosumab therapy in pediatric X‐linked hypophosphatemia (XLH), highlighting coordinated changes in T cell subtypes (Th2, Th17, and Treg) and natural killer cell subtypes (NK2 and NK3) and immune pathways linked to osteoclast differentiation and treatment response.
Yue Xie   +6 more
wiley   +1 more source

Speciation with gene flow

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long   +7 more
wiley   +1 more source

Transcriptomic stress responses in Vaccinium spp. F1 hybrids: Implications for temperature‐resilient cranberry breeding using a crop wild relative

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Climate extremes threaten the sustainability of cranberry production, a culturally and economically important North American crop. This study demonstrates that wild cranberries (Vaccinium oxycoccos) harbor genetic variation that may enhance cold stress resilience when introduced into cultivated cranberry through hybridization.
Audrey Dickinson   +5 more
wiley   +1 more source

Waves of range dynamics and gene flow characterize the biogeographic history of Litsea elongata, a dominant tree in East Asian evergreen broadleaved forests

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Evergreen broadleaved forests (EBLFs) represent an iconic vegetation type in subtropical montane East Asia, but they are experiencing intensifying anthropogenic pressure and increasing habitat fragmentation. Here, using a dominant and widespread tree species characteristic of East Asian EBLFs, we examine its phylogeographic history and evaluate what it
Sheng‐Yuan Qin   +7 more
wiley   +1 more source

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