Results 11 to 20 of about 1,170,509 (350)

Unveiling the immunomodulatory shift: Epithelial-mesenchymal transition Alters immune mechanisms of amniotic epithelial cells

iScience, 2023
Summary: Epithelial-mesenchymal transition (EMT) changes cell phenotype by affecting immune properties of amniotic epithelial cells (AECs). The present study shows how the response to lipopolysaccharide of cells collected pre- (eAECs) and post-EMT (mAECs)
Valeria Di Lollo, Angelo Canciello, Alessia Peserico, Massimiliano Orsini, Valentina Russo, Adrián Cerveró-Varona, Beatrice Dufrusine, Mohammad El Khatib, Valentina Curini, Annunziata Mauro, Paolo Berardinelli, Cathy Tournier, Massimo Ancora, Cesare Cammà, Enrico Dainese, Luana Fiorella Mincarelli, Barbara Barboni   +16 more
doaj   +1 more source

In vitro and in silico parameters for precise cgMLST typing of Listeria monocytogenes

BMC Genomics, 2022
Background Whole genome sequencing analyzed by core genome multi-locus sequence typing (cgMLST) is widely used in surveillance of the pathogenic bacteria Listeria monocytogenes.
Federica Palma, Iolanda Mangone, Anna Janowicz, Alexandra Moura, Alexandra Chiaverini, Marina Torresi, Giuliano Garofolo, Alexis Criscuolo, Sylvain Brisse, Adriano Di Pasquale, Cesare Cammà, Nicolas Radomski   +11 more
doaj   +1 more source

Best practices for the interpretation and reporting of clinical whole genome sequencing

npj Genomic Medicine, 2022
Whole genome sequencing (WGS) shows promise as a first-tier diagnostic test for patients with rare genetic disorders. However, standards addressing the definition and deployment practice of a best-in-class test are lacking.
C. Austin-Tse, V. Jobanputra, D. Perry, D. Bick, R. Taft, E. Venner, R. Gibbs, Ted Young, Sarah Barnett, J. Belmont, N. Boczek, S. Chowdhury, Katarzyna A Ellsworth, S. Guha, S. Kulkarni, Cherisse A. Marcou, Linyan Meng, David R. Murdock, A. Rehman, Elizabeth Spiteri, A. Thomas-Wilson, H. Kearney, H. Rehm   +22 more
semanticscholar   +1 more source

Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues

Nature Reviews Microbiology, 2019
Conor J Meehan, Galo A Goig, Thomas A Kohl   +2 more
exaly   +2 more sources

Recommendations for whole genome sequencing in diagnostics for rare diseases

European Journal of Human Genetics, 2022
In 2016, guidelines for diagnostic Next Generation Sequencing (NGS) have been published by EuroGentest in order to assist laboratories in the implementation and accreditation of NGS in a diagnostic setting.
E. Souche, S. Beltrán, E. Brosens, J. Belmont, M. Fossum, O. Riess, C. Gilissen, A. Ardeshirdavani, G. Houge, M. V. van Gijn, J. Clayton-Smith, M. Synofzik, N. de Leeuw, Z. Deans, Yasemin Dincer, S. Eck, Saskia N. van der Crabben, M. Balasubramanian, H. Graessner, M. Sturm, H. Firth, A. Ferlini, R. Nabbout, E. de Baere, T. Liehr, M. Macek, G. Matthijs, H. Scheffer, P. Bauer, H. Yntema, M. Weiss   +30 more
semanticscholar   +1 more source

Whole Genome Sequencing for Studying Bacillus anthracis from an Outbreak in the Abruzzo Region of Italy

Microorganisms, 2020
Anthrax is a serious infectious disease caused by the gram-positive and spore-forming bacterium Bacillus anthracis. In Italy, anthrax is an endemic disease with sporadic cases each year and few outbreaks, especially in Southern Italy.
Alexandra Chiaverini, Mostafa Y. Abdel-Glil, Jörg Linde, Domenico Galante, Valeria Rondinone, Antonio Fasanella, Cesare Cammà, Nicola D’Alterio, Giuliano Garofolo, Herbert Tomaso   +9 more
doaj   +1 more source

Confirmation of fifth Candida auris clade by whole genome sequencing

Emerging Microbes and Infections, 2022
Candida auris has emerged globally as a multidrug-resistant pathogen causing outbreaks in health care facilities. Whole genome sequencing (WGS) analysis has identified four major clades, while earlier WGS data from a single Iranian isolate suggested the ...
Bram Spruijtenburg, H. Badali, M. Abastabar, H. Mirhendi, S. Khodavaisy, Joobin Sharifisooraki, M. Armaki, Theun de Groot, J. Meis   +8 more
semanticscholar   +1 more source

Whole genome sequencing of elite athletes

Biology of Sport, 2020
Whole genome sequencing (WGS) has great potential to explore all possible DNA variants associated with physical performance, psychological traits and health conditions of athletes.
Eugenia A. Boulygina, Oleg V. Borisov, Elena V. Valeeva, Ekaterina A. Semenova, Elena S Kostryukova, Nikolay A. Kulemin, Andrey K. Larin, Roza M. Nabiullina, Fanis A. Mavliev, Azat M. Akhatov, Oleg N. Andryushchenko, Liliya B. Andryushchenko, Piotr Zmijewski, Edward V. Generozov, Ildus I Ahmetov   +14 more
doaj   +1 more source

Combination of Whole Genome Sequencing and Metagenomics for Microbiological Diagnostics

International Journal of Molecular Sciences, 2022
Whole genome sequencing (WGS) provides the highest resolution for genome-based species identification and can provide insight into the antimicrobial resistance and virulence potential of a single microbiological isolate during the diagnostic process.
Srinithi Purushothaman, M. Meola, A. Egli   +2 more
semanticscholar   +1 more source

Whole Genome Sequencing of Sunflower Root-Associated

Evolutionary Bioinformatics, 2021
In recent times, diverse agriculturally important endophytic bacteria colonizing plant endosphere have been identified. Harnessing the potential of Bacillus species from sunflower could reveal their biotechnological and agricultural importance.
Olubukola Oluranti Babalola, Bartholomew Saanu Adeleke, Ayansina Segun Ayangbenro   +2 more
doaj   +1 more source