Results 211 to 220 of about 1,170,509 (350)

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

Whole genome sequencing of the pulmonary microbiome in interstitial lung disease subtypes. [PDF]

Respir Res
Knudsen KS, Husebø G, Nielsen R, Paytuvi-Gallart A, Malinverni R, Sanseverino W, Lehmann S, Eagan TM.   +7 more
europepmc   +1 more source

Validation of a Genetic Risk Score Combined with Clinical Variables for Predicting Pulmonary Fibrosis in early Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objectives Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). The study aimed to externally validate a genetic risk score (GRS) and a combined risk score for predicting the risk of RA‐associated PF in an independent cohort of early‐RA patients. Methods This study utilized an inception cohort of 1118 patients
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Optimized high-throughput whole-genome sequencing workflow for surveillance of influenza A virus. [PDF]

Genome Med
Licheri M, Mwanga M, Licheri MF, Graaf-Rau A, Sägesser C, Bittel P, Harder T, Suter-Riniker F, Kelly JN, Dijkman R.   +9 more
europepmc   +1 more source

Whole genome sequencing analysis of antibiotic resistant genes of Shigella species: A systematic review and meta-analysis

Basha Ayele, Getenet Beyene, Zeleke Mekonnen, Ahmed Esmael, Abaysew Ayele, Dawit Hailu Alemayehu, Getachew Tesfaye Beyene   +6 more
openalex   +1 more source

Whole-genome sequencing reveals recent and frequent genetic recombination between clonal lineages of Cryphonectria parasitica in western Europe

, 2019
Arthur Demené, Ludovic Legrand, Jérôme Gouzy, Robert Debuchy, Gilles Saint‐Jean, Olivier Fabreguettes, Cyril Dutech   +6 more
openalex   +2 more sources

Transcriptome sequencing and whole genome expression profiling of chrysanthemum under dehydration stress [PDF]

, 2013
Yanjie Xu, Shan Gao, Yingjie Yang, Mingyun Huang, Lina Cheng, Wei Qian, Zhangjun Fei, Junping Gao, Bo Hong   +8 more
openalex   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Whole genome sequencing and annotations of Trametes sanguinea ZHSJ. [PDF]

Sci Data
Lodi RS, Jia X, Yang P, Peng C, Dong X, Han J, Liu X, Wan L, Peng L.   +8 more
europepmc   +1 more source

In Silico Whole Genome Sequencer and Analyzer (iWGS): a Computational Pipeline to Guide the Design and Analysis of de novo Genome Sequencing Studies [PDF]

, 2016
Xiaofan Zhou, David Peris, Jacek Kominek, Cletus P. Kurtzman, Chris Todd Hittinger, Antonis Rokas   +5 more
openalex   +1 more source