Results 111 to 120 of about 3,667,853 (278)

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang   +7 more
wiley   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong   +10 more
wiley   +1 more source

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

open access: yesArthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby   +448 more
wiley   +1 more source

Measurements of the Low-acceleration Gravitational Anomaly from the Normalized Velocity Profile of Gaia Wide Binary Stars and Statistical Testing of Newtonian and Milgromian Theories

open access: yesThe Astrophysical Journal
Low-acceleration gravitational anomaly is investigated with a new method of exploiting the normalized velocity profile $\tilde{v}\equiv {v}_{p}/{v}_{c}$ of wide binary stars as a function of the normalized sky-projected radius s / r _M , where v _p is ...
Kyu-Hyun Chae
doaj   +1 more source

The magnetic fields in Be stars are stronger than previously suggested

open access: yesAstronomy & Astrophysics
Context. Recent observational studies suggest that Be stars most likely are formed through the process of mass transfer in binary systems. In view of the wide consensus that the origin of the magnetic field in stars with radiative envelopes involves ...
Hubrig S.   +3 more
doaj   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

open access: yesArthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch   +6 more
wiley   +1 more source

Bayesian Inference of Gravity through Realistic 3D Modeling of Wide Binary Orbits: General Algorithm and a Pilot Study with HARPS Radial Velocities

open access: yesThe Astrophysical Journal Letters
When 3D relative displacement r and velocity v between the pair in a gravitationally bound system are precisely measured, the six measured quantities at one phase can allow elliptical orbit solutions at a given gravitational parameter G .
Kyu-Hyun Chae
doaj   +1 more source

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule   +4 more
wiley   +1 more source

Probing the Nature of Gravity in the Low-acceleration Limit: Wide Binaries of Extreme Separations with Perspective Effects

open access: yesThe Astrophysical Journal
Recent statistical analyses of wide binaries have revealed a boost in gravitational acceleration with respect to the prediction by Newtonian gravity at low internal accelerations ≲10 ^−9 m s ^−2 .
Youngsub Yoon, Yong Tian, Kyu-Hyun Chae
doaj   +1 more source

The period distribution of close binary systems

open access: yes, 1979
The analysis of the period distribution of eclipsing and spectroscopic binary systems shows the presence of some secondary maxima, which cannot depend on selection effects. These secondary maxima are mainly due to late type stars, as can be seen from the
Farinella P.   +3 more
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