Results 71 to 80 of about 3,140,292 (265)

Targeted Metabolomics for Biomarker Discovery

, 2010
Metabolomics is a truly interdisciplinary field of science, which combines analytical chemistry, platform technology, mass spectrometry, and NMR spectroscopy with sophisticated data analysis.
Hans-Peter Deigner, David P. Enot, Matthias Kohl, Enot, David P., Yuqin Wang, Koal, Therese, William Griffiths, Therese Koal, William J. Griffiths, Wang, Yuqin, Griffiths, William J., Kohl, Matthias, Deigner, Hans-Peter   +12 more
core   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Retinal metabolic events in preconditioning light stress as revealed by wide-spectrum targeted metabolomics [PDF]

Metabolomics, 2017
Light is the primary stimulus for vision, but may also cause damage to the retina. Pre-exposing the retina to sub-lethal amount of light (or preconditioning) improves chances for retinal cells to survive acute damaging light stress.This study aims at exploring the changes in retinal metabolome after mild light stress and identifying mechanisms that may
Chao de La Barca, Juan Manuel, Huang, Nuan-Ting, Jiao, Haihan, Tessier, Lydie, Gadras, Cédric, Simard, Gilles, Natoli, Riccardo, Tcherkez, Guillaume, Reynier, Pascal, Valter, Krisztina   +9 more
openaire   +3 more sources

Ionic Gating of Liquid‐Crystal‐Like Pteridine Assemblies Enables Tunable Light Scattering

Advanced Materials, EarlyView.
Tunable optical properties emerge through developmentally regulated ionic gating, which transforms disordered, ultraviolet (UV)‐absorbing organelles into concentrically ordered, liquid‐crystal‐like light scatterers. By integrating analyses of pteridine composition, potassium‐dependent assembly, hierarchical ultrastructure, and optical behavior, the ...
Sourabh Bera, Zohar Eyal, Yael Noy, Yuval Barzilay, Siddharth Sahoo, Srikant Moharana, Avi Baram, Tali Lerer‐Goldshtein, Neta Varsano, Bar Bader, Lothar Houben, Uwe Heinig, Iddo Pinkas, Moshe Goldsmith, Tamar Unger, Shira Albeck, Andrea Sorrentino, Maxim Itkin, Sergey Malitsky, Ziv Porat, Ido Hadar, Venkata Jayasurya Yallapragada, Dvir Gur   +22 more
wiley   +1 more source

Polyploidization Increases the Lipid Content and Improves the Nutritional Quality of Rice

Plants, 2022
Plant polyploidization is frequently associated with changes in nutrient contents. However, the possible contribution of metabolites to this change has not been investigated by characterizing the metabolite contents of diploid and tetraploid forms of ...
Wei Wang, Qiang Tu, Rongrong Chen, Pincang Lv, Yanqing Xu, Qian Xie, Zhaojian Song, Yuchi He, Detian Cai, Xianhua Zhang   +9 more
doaj   +1 more source

Widely Targeted Metabolomics Reveals the Effects of Soil on the Metabolites in Dioscorea opposita Thunb.

Molecules, 2023
Chinese yam (Dioscorea opposita Thunb. cv. Tiegun), a type of homologous medicinal plant, mainly grows in sandy soil (SCY) and loessial soil (LCY). However, the effects of the soil on the metabolites in SCY and LCY remain unclear. Herein, this study aims to comprehensively elucidate the metabolites in SCY and LCY.
Yang, Lanping, Zhai, Yangyang, Zhang, Zhenzhen, Liu, Zhenzhen, Hou, Baohua, Zhang, Baobao, Wang, Zhenhui   +6 more
openaire   +3 more sources

Emerging Role of Metabolomics in Ovarian Cancer Diagnosis

, 2020
Ovarian cancer is considered a silent killer due to the lack of clear symptoms and efficient diagnostic tools that often lead to late diagnoses. Over recent years, the impelling need for proficient biomarkers has led researchers to consider metabolomics,
Gianmaria Miolo, Asia Saorin, Agostino Steffan, Giuseppe Corona, Emanuela Di Gregorio   +4 more
core   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Widely targeted metabolomics analysis of different Wuyi Shuixian teas and association with taste attributes

Heliyon, 2023
There are two major types of Wuyi Shuixian teas with distinct flavor properties in the market: regular Shuixian, and Laocong Shuixian that is produced from old tea plants with higher sale price. However, the chemical composition difference between these two types of Shuixian teas is still unclear.
Hu Shang, Chensong Zhu, Weijiang Sun
openaire   +3 more sources

Region‐Specific Profiling of the Gut Microbiome and Metabolite Landscape in Response to Dietary Intervention Using Electronics‐Free Ingestible Smart Sampling Capsules

Advanced Materials Technologies, EarlyView.
Region‐specific profiling of the gut microbiome is achieved non‐invasively using electronics‐free ingestible sampling capsules that activate at defined intestinal sites through stimuli‐responsive coatings. Deployed in a porcine dietary intervention model, the capsules resolve spatially distinct, fiber‐driven shifts in microbial composition and short ...
Devendra Sarnaik, Caitlyn Sullivan, Akshay Krishnakumar, Fangxin Chen, Anna Clapp Organski, Wayne W. Campbell, Jay S. Johnson, Tzu‐Wen L. Cross, Rahim Rahimi   +8 more
wiley   +1 more source