Results 91 to 100 of about 3,140,292 (265)

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Using widely targeted metabolomics profiling to explore differences in constituents of three Bletilla species. [PDF]

Sci Rep
Bletilla striata has been used in traditional Chinese medicine for thousands of years to treat a variety of health diseases. Currently, metabolic causes of differences in medicinal values are unknown, due to the lack of a large-scale and comprehensive investigation of metabolites in Bletilla species. In order to gain a better understanding of the major
Xu W, Huang J, Wang P, Yang Y, Fu S, Ying Z, Zhou Z.   +6 more
europepmc   +4 more sources

Targeted livestock metabolomics: a review of liquid chromatography–mass spectrometry-based approaches [PDF]

With the advancement of sophisticated analytical techniques, such as nuclear magnetic resonance spectroscopy and mass spectrometry (MS), metabolomics has become a powerful tool for analyzing and quantifying small molecules in cells, tissues, and ...
Xu, Kangkang, Schwartz-Zimmermann, Heidi E., Berthiller, Franz, Krska, Rudolf   +3 more
core   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

Widely targeted metabolomics analysis to reveal the metabolite profiles of the medicinal and food homologous Rubus chingii Hu

Medicinal and dietary R. chingii Hu were selected, and their metabolites were analyzed by widely targeted metabolomics methodsTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Qian, C (via Mendeley Data), Qian, Can
core   +1 more source

Targeted metabolomics of CSF in healthy individuals and patients with secondary progressive multiple sclerosis using high-resolution mass spectrometry

, 2020
Introduction: Standardized commercial kits enable targeted metabolomics analysis and may thus provide an attractive complement to the more explorative approaches.
Khoonsari, PE, Carlsson, H, Kultima, Kim, Emami Khoonsari, Payam,, Emami Khoonsari, Payam, Åkerfeldt, Torbjörn,, Burman, J, Herman, Stephanie,, Akerfeldt, T, Svenningsson, Anders, Abujrais, S, Svenningsson, A,, Abujrais, Sandy, Herman, Stephanie, Burman, Joachim, Burman, Joachim,, Carlsson, Henrik, Abujrais, Sandy,, Carlsson, Henrik,, Svenningsson, Anders,, Kultima, K, Kultima, Kim,, Herman, S, Åkerfeldt, Torbjörn   +23 more
core   +1 more source

Inter-laboratory reproducibility of fast gas chromatography-electron impact-time of flight mass spectrometry (GC-EI-TOF/MS) based plant metabolomics [PDF]

, 2009
The application of gas chromatography¿mass spectrometry (GC¿MS) to the `global¿ analysis of metabolites in complex samples (i.e. metabolomics) has now become routine.
Dunn, Warwick, Luedemann, A., Lüdemann, A., Arjen Lommen, Goodacre, R., Lommen, Arjen, Lorraine Kay, Dunn, Warwick B., Joachim Kopka, Allwood, J. William, de Koning, S., Erban, Alexander, Kay, Lorraine, Sjaak de Koning, Ralf Löscher, Erban, A., Alexander Erban, Royston Goodacre, de Koning, Sjaak, Löscher, R., Goodacre, Royston, Allwood, J., Kay, L., Allwood, J.W., Dun, W.B., Lommen, A., Kopka, J., Koning, S., Alexander Luedemann, J. William Allwood, Luedemann, Alexander, Dunn, Warwick B, Dunn, W., Kopka, Joachim, Allwood, James, Löscher, Ralf, Warwick B. Dunn   +36 more
core   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Classification of farming systems by NMR widely targeted metabolomics: A cauliflower case study

Journal of Food Composition and Analysis
Organic and conventional farming systems follow a set of specific rules and consumers usually pay an extra price for organic products, since they are associated with a higher quality. Nuclear magnetic resonance allows the analysis of the metabolome in a fast, non-destructive, and automatic way, with high coverage of chemical families and accurate ...
Brigante, F., Solovyev, P., Fabroni, S., Campanelli, G., Montemurro, F., Bontempo, L.   +5 more
openaire   +2 more sources

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source