Results 111 to 120 of about 75,765 (265)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Genomic introgressions from wild relatives in the wheat genome alter meiotic dynamics in inter-varietal hybrids. [PDF]

Plant J
Yan L, Chéron F, Nadaud I, Hao M, Liu D, Sourdille P.   +5 more
europepmc   +1 more source

Genomic characterization and gene bank curation of Aegilops: the wild relatives of wheat. [PDF]

Front Plant Sci, 2023
Adhikari L, Raupp J, Wu S, Koo DH, Friebe B, Poland J.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Morphology of Chinese Chive and Onion (Allium; Amaryllidaceae) Crop Wild Relatives: Taxonomical Relations and Implications. [PDF]

Plants (Basel)
Jo MS, Kim JE, Chu YR, Chung GY, Na CS.
europepmc   +1 more source

Complementary Analysis and Implementation Plan for Conservation of Crop Wild Relatives in Finland. [PDF]

Plants (Basel), 2023
Fitzgerald H, Kiviharju E, Palmé A, Hyvärinen M.   +3 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Biofortification of dietary fibre: exploring enhanced β-glucan and arabinoxylan content in a panel of <i>Triticum</i> and wild relatives. [PDF]

Front Plant Sci
Kapoor P, Panigrahi S, Singh Y, Kumar S, Singh KP, Jan F, Mir RR, Kumar U.   +7 more
europepmc   +1 more source

Impact of Heat and Drought Stress on Grasspea and Its Wild Relatives. [PDF]

Plants (Basel), 2023
Aloui K, Choukri H, El Haddad N, Gupta P, El Bouhmadi K, Emmrich PMF, Singh A, Edwards A, Maalouf F, Bouhlal O, Staples J, Kumar S, Kumar S.   +12 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source