Results 131 to 140 of about 76,572 (264)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Wild relatives to improve heat tolerance of cultivated quinoa (Chenopodium quinoa): pollen viability and grain number. [PDF]

J Exp Bot
Xu J, Farooq HU, Hashim M, Rey E, Curti R, Morris A, Maughan PJ, Jellen EN, Jarvis DE, Bertero D, Melino V, Tester M.   +11 more
europepmc   +1 more source

Population Genomics of Domesticated Cucurbita ficifolia Reveals a Recent Bottleneck and Low Gene Flow with Wild Relatives. [PDF]

Plants (Basel), 2023
Aguirre-Dugua X, Barrera-Redondo J, Gasca-Pineda J, Vázquez-Lobo A, López-Camacho A, Sánchez-de la Vega G, Castellanos-Morales G, Scheinvar E, Aguirre-Planter E, Lira-Saade R, Eguiarte LE.   +10 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Nordic Crop Wild Relative conservation

, 2019
Anna Palmé, Heli Fitzgerald, Jens Weibull, Kristina Bjureke, Kaija Eisto, Dag En-dresen, Jenny Hagenblad, Marko Hyvärinen, Elina Kiviharju, Birgitte Lund, Morten Rasmussen, Hjörtur Þorbjörnsson   +11 more
openaire   +2 more sources

A Methodological Approach for Evaluating the Genotypic Variation for Physiological Adaptation of Potato Wild Relatives for Heat Tolerance Breeding. [PDF]

Plants (Basel)
Bashir I, Nicolao R, Shimoia EP, do Amarante L, Castro CM, Heiden G.   +5 more
europepmc   +1 more source

New receptors for common MAMPs: Can wild relatives save citrus from disease? [PDF]

Plant Physiol, 2023
McMillan HM.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Genomic resources for crop wild relatives are critical for perennial fruit breeding and conservation. [PDF]

Am J Bot
Migicovsky Z.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source