Results 121 to 130 of about 76,572 (264)

Complementary Analysis and Implementation Plan for Conservation of Crop Wild Relatives in Finland. [PDF]

Plants (Basel), 2023
Fitzgerald H, Kiviharju E, Palmé A, Hyvärinen M.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Biofortification of dietary fibre: exploring enhanced β-glucan and arabinoxylan content in a panel of <i>Triticum</i> and wild relatives. [PDF]

Front Plant Sci
Kapoor P, Panigrahi S, Singh Y, Kumar S, Singh KP, Jan F, Mir RR, Kumar U.   +7 more
europepmc   +1 more source

Genomic conservation of crop wild relatives: A case study of citrus. [PDF]

PLoS Genet, 2023
Wang N, Cao S, Liu Z, Xiao H, Hu J, Xu X, Chen P, Ma Z, Ye J, Chai L, Guo W, Larkin RM, Xu Q, Morrell PL, Zhou Y, Deng X.   +15 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Interspecific hybridization history of <i>Vaccinium</i> berry crops and potential in wild relatives. [PDF]

Hortic Res
Khalid AM, Benevenuto J, Lyrene PM, Munoz PR.   +3 more
europepmc   +1 more source

Impact of Heat and Drought Stress on Grasspea and Its Wild Relatives. [PDF]

Plants (Basel), 2023
Aloui K, Choukri H, El Haddad N, Gupta P, El Bouhmadi K, Emmrich PMF, Singh A, Edwards A, Maalouf F, Bouhlal O, Staples J, Kumar S, Kumar S.   +12 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Genotype × Environment Effects in Three Wild Relatives of Sorghum From Australia. [PDF]

Plant Environ Interact
Myrans H, Chithrarachchige D, Henry RJ, Norton S, Gleadow RM.   +4 more
europepmc   +1 more source

Genetic Incompatibilities and Evolutionary Rescue by Wild Relatives Shaped Grain Amaranth Domestication. [PDF]

Mol Biol Evol, 2023
Gonçalves-Dias J, Singh A, Graf C, Stetter MG.   +3 more
europepmc   +1 more source