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Microbial Evolution: Stalking the Wild Bacterial Species [PDF]

Current Biology, 2008
A recent report suggests that, when habitats are disturbed, bacterial populations that would be considered to be separate species can merge, reversing the process of speciation. But, for bacteria, 'species' remains undefined and undefinable.
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A high-quality chromosome-level genome assembly of herbaceous bamboo species Lithachne pauciflora

Scientific Data
Lithachne pauciflora is a herbaceous bamboo species characterized by its short height, low degree of lignification, and dimorphic florets, making it a special model for studying the key trait evolution in bamboo.
Ke-Cheng Qian, Jun-Feng Liu, Yang Yang, Cen Guo, Zhen-Hua Guo   +4 more
doaj   +1 more source

Wild Chimpanzees Infected with 5PlasmodiumSpecies

Emerging Infectious Diseases, 2010
Data are missing on the diversity of Plasmodium spp. infecting apes that live in their natural habitat, with limited possibility of human-mosquito-ape exchange. We surveyed Plasmodium spp. diversity in wild chimpanzees living in an undisturbed tropical rainforest habitat and found 5 species: P. malariae, P. vivax, P. ovale, P. reichenowi, and P. gaboni.
Kaiser, Marco, Löwa, Anna, Ulrich, Markus, Ellerbrok, Heinz, Goffe, Adeelia S., Blasse, Anja, Zommers, Zinta, Couacy-Hymann, Emmanuel, Babweteera, Fred, Zuberbühler, Klaus, Metzger, Sonja, Geidel, Sebastian, Boesch, Christophe, Gillespie, Thomas R., Leendertz, Fabian   +14 more
openaire   +5 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Positive selection and relaxed purifying selection contribute to rapid evolution of male-biased genes in a dioecious flowering plant

eLife
Sex-biased genes offer insights into the evolution of sexual dimorphism. Sex-biased genes, especially those with male bias, show elevated evolutionary rates of protein sequences driven by positive selection and relaxed purifying selection in animals ...
Lei Zhao, Wei Zhou, Jun He, De-Zhu Li, Hong-Tao Li   +4 more
doaj   +1 more source

Molecular and Cytogenetic Characterization of Wild Musa Species

PLOS ONE, 2015
The production of bananas is threatened by rapid spreading of various diseases and adverse environmental conditions. The preservation and characterization of banana diversity is essential for the purposes of crop improvement. The world's largest banana germplasm collection maintained at the Bioversity International Transit Centre (ITC) in Belgium is ...
Cizkova, J., Hribova, E., Christelova, P., Van den houwe, Ines, Hakkinnen, M., Roux, N., Swennen, Rony, Dolezel, J.   +7 more
openaire   +8 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Evolutionary Character of Alternative Splicing in Plants

Bioinformatics and Biology Insights, 2015
Alternative splicing (AS) is one of the most important ways to enhance the functional diversity of genes. Huge amounts of data have been produced by microarray, expressed sequence tag, and RNA-seq, and plenty of methods have been developed specifically ...
Chengjun Zhang, Hong Yang, Huizhao Yang
doaj   +1 more source