Results 281 to 290 of about 13,679,770 (330)
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Neurologic Clinics, 2020
Purpose of review The aim of this article is to review recent developments in the areas of the disease features and treatment of Wilson disease, and survey disorders that share its pathophysiology or clinical symptoms. Recent findings Knowledge of the clinical spectrum of Wilson ...
Jeff M Bronstein
exaly +4 more sources
Purpose of review The aim of this article is to review recent developments in the areas of the disease features and treatment of Wilson disease, and survey disorders that share its pathophysiology or clinical symptoms. Recent findings Knowledge of the clinical spectrum of Wilson ...
Jeff M Bronstein
exaly +4 more sources
Long-term Outcomes of Patients With Wilson Disease in a Large Austrian Cohort
Clinical Gastroenterology and Hepatology, 2014 BACKGROUND & AIMS Wilson disease is an autosomal recessive disorder that affects copper metabolism, leading to copper accumulation in liver, central nervous system, and kidneys. There are few data on long-term outcomes and survival from large cohorts;
Sandra Beinhardt +2 more
exaly +2 more sources
Hepatobiliary malignancies in Wilson disease
Liver International, 2015 Reports of hepatobiliary malignancies in Wilson disease are sparse. The aim of this study was to evaluate hepatobiliary malignancies in Wilson disease patients concerning the clinical course of tumour disease and pathological analysis of tumour tissue ...
Jan Pfeiffenberger +2 more
exaly +2 more sources
Current Treatment Options in Neurology, 2000
Appropriate anticopper therapy for Wilson's disease is the critical element in halting progression of the disease and allowing patient recovery. Selection of the drug or drugs to use for a particular patient depends on the stage of the disease (ie, initial acutely ill patient versus chronic maintenance patient) and the type of presentation (ie ...
G, Loudianos, J D, Gitlin
+9 more sources
Appropriate anticopper therapy for Wilson's disease is the critical element in halting progression of the disease and allowing patient recovery. Selection of the drug or drugs to use for a particular patient depends on the stage of the disease (ie, initial acutely ill patient versus chronic maintenance patient) and the type of presentation (ie ...
G, Loudianos, J D, Gitlin
+9 more sources
Relative exchangeable copper: A valuable tool for the diagnosis of Wilson disease
Liver International, 2018Jérôme Dumortier +2 more
exaly +2 more sources
Clinical Liver Disease, 2022
The silver anniversary of the discovery of the Wilson disease gene ATP7B was a couple of years ago, and we continue to make progress both in our understanding of copper transportation using animal models as well as earlier diagnosis by availing of ...
N. Kerkar, A. Rana
semanticscholar +1 more source
The silver anniversary of the discovery of the Wilson disease gene ATP7B was a couple of years ago, and we continue to make progress both in our understanding of copper transportation using animal models as well as earlier diagnosis by availing of ...
N. Kerkar, A. Rana
semanticscholar +1 more source
Wilson Disease: An Overview and Approach to Management.
Neurologic clinics, 2020Wilson's disease is one of the few preventable movement disorders in which there are therapies that modify disease progression. This disease is caused by copper overload caused by reduced copper excretion secondary to genetic mutations in the ATP7B gene.
Caitlin Mulligan, J. Bronstein
semanticscholar +1 more source
Seminars in Neurology, 2023
AbstractWilson's disease (WD) can present with liver disease, neurological deficits, and psychiatric disorders. Results of genetic prevalence studies suggest that WD might be much more common than previously estimated. Early recognition of WD remains challenging because it is a great imitator and requires a high index of suspicion for correct and ...
Manida, Wungjiranirun, Kaveh, Sharzehi
openaire +2 more sources
AbstractWilson's disease (WD) can present with liver disease, neurological deficits, and psychiatric disorders. Results of genetic prevalence studies suggest that WD might be much more common than previously estimated. Early recognition of WD remains challenging because it is a great imitator and requires a high index of suspicion for correct and ...
Manida, Wungjiranirun, Kaveh, Sharzehi
openaire +2 more sources
2006
Wilson disease is a recessively inherited disorder of copper transport. Clinical features are highly variable, with any combination of neurological, hepatic or psychiatric illness. The age of onset varies from 3 to 50 years of age. Diagnosis is challenging because no specific combination of clinical or biochemical features is necessarily definitive ...
E A, Roberts, D W, Cox
openaire +4 more sources
Wilson disease is a recessively inherited disorder of copper transport. Clinical features are highly variable, with any combination of neurological, hepatic or psychiatric illness. The age of onset varies from 3 to 50 years of age. Diagnosis is challenging because no specific combination of clinical or biochemical features is necessarily definitive ...
E A, Roberts, D W, Cox
openaire +4 more sources