Results 31 to 40 of about 1,098,240 (291)
Medicine, 1992 Wilson disease is an inherited disorder of copper metabolism. Progress has been made in establishing the location of the gene on the long arm of chromosome 13, and in finding nearby probes that can be used to identify affected sibs of newly diagnosed patients. However, the gene has not been cloned, and the molecular nature of the defect remains unknown.
G J, Brewer, V, Yuzbasiyan-Gurkan
openaire +2 more sources
Diabetes mellitus and necrotizing fasciitis – a deadly combination; case report [PDF]
, 2020 Necrotizing fasciitis is a rapidly destructive affliction of soft tissues, with a mortality rate that may reach 73% of the cases. It is characterized by a progressive inflammation and extended necrosis of the subcutaneous tissue and the fascia ...
Andronache, Liliana Florina +8 more
core +3 more sources
The Turkish Journal of Gastroenterology, 2021 Background: Wilson disease (WD) is an autosomal recessive inherited disorder of copper (Cu2+) metabolism, resulting in Cu2+ accumulation and liver and central nervous system toxicity.
Emine Melis Yücel +7 more
doaj +1 more source
Life history and mating systems select for male biased parasitism mediated through natural selection and ecological feedbacks [PDF]
, 2010 Males are often the "sicker" sex with male biased parasitism found in a taxonomically diverse range of species. There is considerable interest in the processes that could underlie the evolution of sex-biased parasitism.
Bacelar, Flora S. +2 more
core +5 more sources
Copper – a novel stimulator of autophagy
Cell Stress, 2020 Toxic copper accumulation causes Wilson disease, but trace amounts of copper are required for cellular and organismal survival. In a recent paper Tsang et al.
Hans Zischka, Guido Kroemer
doaj +1 more source
Climate Change and Highland Malaria: Fresh Air for a Hot Debate [PDF]
, 2010 In recent decades, malaria has become established in zones at the margin of its previous distribution, especially in the highlands of East Africa.
Chaves, L.F., Koenraadt, C.J.M.
core +2 more sources
Bioengineering, 2019 Wilson Disease is a rare autosomal recessive liver disorder in humans. Although its clinical presentation and age of onset are highly variable, hallmarks include signs of liver disease, neurological features and so-called Kayser-Fleischer rings in the ...
Hedwig S. Kruitwagen +2 more
doaj +1 more source
The hereditary angioedema burden of illness study in Europe (HAE-BOIS-Europe) : background and methodology [PDF]
, 2012 Background: Hereditary angioedema (HAE) is a rare but serious disease marked by swelling attacks in the extremities, face, trunk, airway, or abdominal areas that can be spontaneous or the result of trauma and other triggers.
Aygören-Pürsün, Emel +7 more
core +2 more sources
Sideroblastic Anemia in a Young Woman Being Treated for Wilson Disease
Annals of Internal Medicine: Clinical Cases, 2023 D-penicillamine and zinc are both useful in the treatment of Wilson disease. Both drugs can cause pancytopenia by the direct toxic effect on the marrow or sideroblastic anemia caused by hyperzincemia-induced hypocupremia. Although serum copper levels are
Vivien Mak, Kate Leung, Wai-lim Yiu
doaj +1 more source
The impact of heat on mortality and morbidity in the Greater Metropolitan Sydney Region: A case crossover analysis [PDF]
, 2015 Background: This study examined the association between unusually high temperature and daily mortality (1997-2007) and hospital admissions (1997-2010) in the Sydney Greater Metropolitan Region (GMR) to assist in the development of targeted health ...
Abu-Rayya, Hisham +7 more
core +1 more source