Results 51 to 60 of about 9,070,941 (298)

Experimental Study of Mitigation of Wind-Induced Vibration in Asymmetric Cable-Stayed Bridge Using Sharp Wind Fairings

Applied Sciences, 2021
This paper investigated the aerodynamic response features of an asymmetric cable-stayed bridge. The wind resistance design parameters for judging the response were first determined, afterwards the bridge dynamic characteristics were analyzed for ...
Guohui Zhao, Zhichao Wang, Shuo Zhu, Jianming Hao, Jun Wang   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A novel partitioned numerical coupling between vortex particle method–structure–smoothed particle hydrodynamics models for wind-induced vibration analysis

Results in Engineering
The article introduces a novel weakly-partitioned numerical coupling method implemented to analyze the wind-induced response of low-damped structures incorporating a Tuned Liquid Damper (TLD).
Victor Vîlceanu, Samir Chawdhury, Guido Morgenthal   +2 more
doaj   +1 more source

Evaluation of Wind-Induced Response Bounds of High-Rise Buildings Based on a Nonrandom Interval Analysis Method

Shock and Vibration, 2018
The traditional wind-induced response analysis of high-rise buildings conventionally considers the wind load as a stationary stochastic process. That is, for a certain wind direction angle, the reference wind speed (usually refers to the mean wind speed ...
Xianglei Wei, An Xu, Ruohong Zhao
doaj   +1 more source

Effect of Wind Environment on the response of Buildings in Oman

Sultan Qaboos University Journal for Science, 1998
An investigation has been carried out to study the effect of the wind parameters on the response of multistory buildings subjected to wind induced forces.
Mohammed Qamaruddin, Salem K. Al-Oraimi
doaj   +1 more source

Calculation of the Dynamic Wind-Induced Deflection Response of Overhead Lines: Establishment and Analysis of the Multi-Rigid-Body Model

IEEE Access, 2020
Wind-induced deflection flashover severely endangers the normal operation of overhead transmission lines. This paper proposes a multi-rigid-body model for the accurate and efficient calculation of the dynamic wind-induced deflection response of overhead ...
Xin Hu, Zhangqi Wang, Rui Tian
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A study of the statistical approach to wind loading [PDF]

, 1975
Includes bibliographical references.This study is concerned with the prediction of the maximum probable response of structures in the along-wind direction.
Watson, Bjorn Hugh Henry
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source