Results 51 to 60 of about 463,017 (306)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Stochastic Dynamic Response Analysis of Spar-Type Wind Turbines with Catenary or Taut Mooring Systems [PDF]
, 2011 Floating wind turbines can be the most practical and economical way to extract the vast offshore wind energy resources at deep and intermediate water depths. The Norwegian Ministry of Petroleum and Energy is strongly committed to developing offshore wind
Karimirad, Madjid
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Latin American Journal of Solids and StructuresUse of Tuned Mass Dampers (TMDs) to reduce the wind-induced torsional response of structures has been investigated in the literature by assuming that the wind excitations can be approximated by harmonic forces or white noise random processes; however ...
A. Pozos-Estrada, H.P. Hong
doaj +1 more source
Effect of Wind Environment on the response of Buildings in Oman
Sultan Qaboos University Journal for Science, 1998 An investigation has been carried out to study the effect of the wind parameters on the response of multistory buildings subjected to wind induced forces.
Mohammed Qamaruddin, Salem K. Al-Oraimi
doaj +1 more source
Advances in Materials Science and Engineering, 2022 Steel arch bridges with inclined arch ribs under strong wind fields are prone to fatigue damage due to the stress concentration at the position of hanger connections.
You-Hua Su, Yan-Ru Wu, Qing Sun
doaj +1 more source
Scaling in long term data sets of geomagnetic indices and solar wind ϵ as seen by WIND spacecraft [PDF]
, 2003 We study scaling in fluctuations of the geomagnetic indices (AE, AU, and AL) that provide a measure of magnetospheric activity and of the ε parameter which is a measure of the solar wind driver.
Chapman, S.C. +8 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Wind-Induced Response of an L-Shaped Cable Support Glass Curtain Wall
Shock and Vibration, 2017 Due to its flexibility, cable support glass curtain wall is sensitive to wind loads and its wind-induced dynamic response has attracted more and more attention recently.
Yan Yu, Tao Liu, Qilin Zhang, Bin Yang
doaj +1 more source