Results 71 to 80 of about 463,017 (306)

Wind-Induced Response Analysis and Fatigue Life Prediction of a Hybrid Wind Turbine Tower Combining an Upper Steel Tube with a Lower Steel Truss

Buildings
Based on the WindPACT-3MW wind turbine tower commonly used in wind power engineering, a finite element model (FEM) of a hybrid wind turbine tower combining an upper steel tube with a lower steel truss is designed and established.
Meng Zhang, Chenhao Xie, Tianxiang Li, Md Nayim Hossain, Guifeng Zhao   +4 more
doaj   +1 more source

The fundamental human response to wind-induced building motion

, 2017
This paper identifies seven areas where an increase in our fundamental understanding of the human response to building motion will facilitate the design of next-generation serviceability criteria for wind-induced building motion.
Lamb, Steven (R18264), Kwok, Kenny C. S. (R14040)   +1 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Wind-Induced Response and Fatigue Analysis of Corona Ring in Power Equipment

Applied Sciences
With the increasingly significant impact of high-wind-load environments on power equipment, the wind stability of the corona ring has become a key issue to ensure the safe operation of power grids.
Zhihui Wang, Qijun Liang, Hailong Jia, Gaofei Liu, Bohai Tian, Chenzhi Cai, Zixun Zhou, Shaopeng Xu   +7 more
doaj   +1 more source

Restoring wind-induced responses of supertall buildings

Scilight
Machine learning model can reconstruct missing displacement measurements of supertall buildings during typhoons, enabling real-time structural health monitoring.
openaire   +1 more source

Aerodynamics of wind turbines

, 2011
PhDThe study of rotor blade aerodynamic performances of wind tur- bine has been presented in this thesis. This study was focused on aero- dynamic effects changed by blade surface distribution as well as grid solution along the airfoil.
Emrah Kulunk, Horikiri, Kana
core   +1 more source

Reconnection in a rotation-dominated magnetosphere and its relation to Saturn's auroral dynamics [PDF]

, 2005
peer reviewed[1] The first extended series of observations of Saturn's auroral emissions, undertaken by the Hubble Space Telescope in January 2004 in conjunction with measurements of the upstream solar wind and interplanetary magnetic field ( IMF) by the
D. Grodent (7590713), Badman, S. V., Grodent, Denis, J. T. Clarke (7590707), S. W. H. Cowley (7590302), Gérard, J.-c., C.M. Jackman (7590716), Bunce, E.J., Badman, Sarah V., Clarke, J. T., Milan, S.E., Jackman, C. M., Jackman, C.M., Gérard, Jean-Claude, Badman, S.V., Yeoman, T. K., Tim K. Yeoman (7583066), Milan, S. E., Jackman, Caitriona M., Cowley, S.W.H., Grodent, D., E. J. Bunce (7590470), Steve E. Milan (7589666), S. V. Badman (7590704), J.-C. Gérard (7590710), Clarke, J.T., Cowley, S. W. H., Bunce, E. J., Gérard, J.C., Yeoman, T.K.   +29 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Dynamic response of temporary structures due to wind loading

, 2015
Due to the lack of an international standard for the design of temporary stage structures, there have been several instances where temporary stage structures have failed and resulted in injury or death during strong wind events (Tomasetti, 2012).
Bishay, A. (x), Pagano, T., Kwok, Kenny C. S. (R14040), Dang, J. (x)   +3 more
core