Results 141 to 150 of about 1,752,983 (309)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Nonlinear EngineeringSensitivity evaluation of nonlinear systems to system parameters is critically important in nonlinear dynamics, though current focuses in the field are mainly on the sensitive dependence of nonlinear systems upon initial conditions.
Xia Dandan, Dai Liming
doaj +1 more source
, 2015 47 office workers located on high floors and 53 office workers on or near the ground floor in Wellington, New Zealand, completed 1,909 short online surveys across a period of 8 months.
Lamb, Steven (R18264) +2 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Turbulence Length Scales in a Boundary Layer Wind Tunnel
, 2001 Turbulence length scales are important parameters affecting the aerodynamic characteristics and response of structures in wind flow. It is therefore essential to simulate the wind velocity profile models in scaling these turbulence length scale ...
Cheung, John C. K. +1 more
core
Tribal Wind Assessment by the Eastern Shoshone Tribe of the Wind River Reservation
, 2009 The Tribes, through its consultant and advisor, Distributed Generation Systems (Disgen) -Native American Program and Resources Division, of Lakewood CO, assessed and qualified, from a resource and economic perspective, a wind energy generation facility ...
Stump, Raphaella Q. +2 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Journal of Engineering and Applied ScienceThe cleanliness of gear oil has a significant impact on the reliability and service life of wind turbine gearboxes, and often, it is the human factor, unsteady maintenance practices, and weak policy support that are responsible for the oil's compromised ...
Biyu Chen +6 more
doaj +1 more source