Results 61 to 70 of about 6,155,302 (304)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Wind Farm Wakes from SAR and Doppler Radar
We retrieve atmospheric wake characteristics at the wind farm Westermost Rough from Sentinel-1 Synthetic Aperture Radar (SAR) images. For the first time, co-located reference measurements of the full flow field around the wind farm are available from ...
Tobias Ahsbahs +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Select Committee on Wind Turbines final report [PDF]
The committee recommends the Commonwealth Government create an Independent Expert Scientific Committee on Industrial Sound responsible for providing research and advice to the Minister for the Environment on the impact on human health of audible noise ...
Select Committee on Wind Turbines
core
Comparison of OpenFOAM and EllipSys3D for neutral atmospheric flow over complex terrain [PDF]
The flow solvers OpenFOAM and EllipSys3D are compared in the case of neutral atmospheric flow over terrain using the test cases of Askervein and Bolund hills.
D. Cavar +7 more
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Power curve and wake analyses of the Vestas multi-rotor demonstrator [PDF]
Numerical simulations of the Vestas multi-rotor demonstrator (4R-V29) are compared with field measurements of power performance and remote sensing measurements of the wake deficit from a short-range WindScanner lidar system.
M. P. van der Laan +11 more
doaj +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source

