Results 71 to 80 of about 31,789 (263)

Research on the impact of irregular structure group construction on rail transit bridge piers and its response to wind load. [PDF]

Sci Rep, 2023
Wang Y, Chen Z, Qi Y.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Wind turbine load optimization control and verification based on wind speed estimator with time series broad learning system method

IET Control Theory & Applications
With the rapid development of wind power, the power performance and mechanical load characteristics of wind turbine are simultaneously considered and focused.
Deyi Fu, Shiyao Qin, Lingxing Kong, Yang Xue, Lice Gong, Anqing Wang   +5 more
doaj   +1 more source

Heliostat Consortium: Gap Analysis on Wind Load for Achieving a Fully Competitive Heliostat Industry

SolarPACES Conference Proceedings
The Heliostat Consortium (HelioCon) Wind Load Subtask was initiated with the aim of bringing research work pertaining to wind load measurement, characterization, and prediction taking place across several tasks, including Advanced Manufacturing ...
Matthew Emes, Shashank Yellapantula, Jeremy Sment, Kenneth Armijo, Matthew Muller, Mark Mehos, Randy Brost, Maziar Arjomandi   +7 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Dynamic performance improvement of standalone battery integrated PMSG wind energy system using proportional resonant controller

Engineering Science and Technology, an International Journal, 2017
The load voltage and frequency should be controlled under steady state and transient conditions in off grid applications. Power quality and power management is very important task for rural communities under erratic wind and load conditions.
Dileep Kumar Varma Sagiraju, Y.P. Obulesu, Sai Babu Choppavarapu   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Dynamic characteristics analysis of planetary gear system with internal and external excitation under turbulent wind load. [PDF]

Sci Prog, 2021
Yang H, Li X, Xu J, Yang Z, Chen R.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Compilation of the Test Load Spectrum of Wind Power Gearbox based on the Random Wind Speed Model

Jixie chuandong, 2015
In order to compile the load spectrum for dynamic characteristic and fatigue life test of wind turbine gear transmission system,the external random wind load is obtained on the basis of simulating reality wind speed and aerodynamics theory,and by using ...
Xu Fang, Zhou Zhigang
doaj