Results 121 to 130 of about 288,988 (304)
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Analytical investigation of wind loads on heliostats
Revue des Énergies Renouvelables, 2016 Applications of Heliostats for solar power tower plants increased in the recent years. Most of the solar power tower plants installed are on flat terrain and they may be subjected to wind loads.
H. Bendjebbas +2 more
doaj
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Study on crashworthiness of offshore wind turbines under different wind loads
Jixie qiangduObjectiveOffshore wind turbines are exposed to the risk of collision with vessels, where the effect of wind loads cannot be ignored. However, existing studies tend to adopt steady-state wind loads, which are inconsistent with actual conditions.MethodsBy ...
LIU Kunpeng +4 more
doaj
Effects of rotor location, coning, and tilt on critical loads in large wind turbines [PDF]
Several large (1500 kW) horizontal rotor configurations were analyzed to determine the effects on dynamic loads of upwind downwind rotor locations, coned and radial blade positions, and tilted and horizontal rotor axis positions.
Janetzke, D. C., Spera, D. A.
core +1 more source
Structural analysis considerations for wind turbine blades [PDF]
, 1979 Approaches to the structural analysis of wind turbine blade designs are reviewed. Specifications and materials data are discussed along with the analysis of vibrations, loads, stresses, and failure ...
Spera, D. A.
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Wind loads on flat plate photovoltaic array fields (nonsteady winds) [PDF]
Techniques to predict the dynamic response and the structural dynamic loads of flat plate photovoltaic arrays due to wind turbulence were analyzed. Guidelines for use in predicting the turbulent portion of the wind loading on future similar arrays are ...
Miller, R. D., Zimmerman, D. K.
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source