Results 61 to 70 of about 288,653 (304)
Experimental Investigation of Local Wind Effects on Façade Scaffolding Structures
Applied SciencesWind is one of the main environmental loads acting on temporary scaffolding structures, yet current design codes apply simplified assumptions regarding its distribution.
Paulina Jamińska-Gadomska +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Wind models for the NSTS ascent trajectory biasing for wind load alleviation [PDF]
New concepts are presented for aerospace vehicle ascent wind profile biasing. The purpose for wind biasing the ascent trajectory is to provide ascent wind loads relief and thus decrease the probability for launch delays due to wind loads exceeding ...
Adelfang, S. I. +3 more
core +1 more source
Modelling of firm offer from combined wind and hydro generations [PDF]
, 2019 This paper analyses the impact of a firm combined offer by wind and small hydro generators located in the river chain, with a view to address the intermittency of wind generators.
Chakrabarti, Bhujanga
core
CFD and aeroelastic analysis of the MEXICO wind turbine [PDF]
, 2014 This paper presents an aerodynamic and aeroelastic analysis of the MEXICO wind turbine, using the compressible HMB solver of Liverpool. The aeroelasticity of the blade, as well as the effect of a low-Mach scheme were studied for the zero-yaw 15m/s wind ...
Barakos, G. +5 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
BuildingsIn this study, we developed a wind load calculation program (WCP) capable of predicting wind loads with relative precision during the preliminary design phase.
Dong-Hyeon Shin, Young-Cheol Ha
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Prediction of low frequency and impulsive sound radiation from horizontal axis wind turbines [PDF]
, 1981 Theoretical models to predict the radiation of low frequency and impulsive sound from horizontal axis wind turbines due to three sources: (1) steady blade loads; (2) unsteady blade loads due to operation in a ground shear; (3) unsteady loads felt by the ...
Harris, W. L. +2 more
core +1 more source