Results 91 to 100 of about 3,189,300 (321)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Numerical Study of Nacelle Wind Speed Characteristics of a Horizontal Axis Wind Turbine under Time-Varying Flow

Energies, 2019
Nacelle wind speed transfer function (NTF) is usually used for power prediction and operational control of a horizontal axis wind turbine. Nacelle wind speed exhibits high instability as it is influenced by both incoming flow and near wake of a wind ...
Xiaodong Wang, Yunong Liu, Luyao Wang, Lin Ding, Hui Hu   +4 more
doaj   +1 more source

Wind Speed Data Analysis for Various Seasons during a Decade by Wavelet and S transform [PDF]

arXiv, 2013
The appropriate weather prediction is a challenging task and it can be feasible with proper wind speed fluctuation analysis. In this current paper daubechies-4 wavelet is used to analyze the winter wind speed fluctuations due to lesser agitated wind data samples of winter.
arxiv  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

A Review on the Building Wind Impact through On-site Monitoring in Haeundae Marine City: 2021 12th Typhoon OMAIS Case Study

한국해양공학회지, 2021
Overcrowding of high-rise buildings in urban zones change the airflow pattern in the surrounding areas. This causes building wind, which adversely affects the wind environment.
Jongyeong Kim, Byeonggug Kang, Yongju Kwon, Seungbi Lee, Soonchul Kwon   +4 more
doaj   +1 more source

Wind Speed Prediction Model Using LSTM and 1D-CNN

Journal of Signal Processing, 2018
This paper describes a prediction method for wind speed us-ing a neural network and an investigation of the structure of the network. Generally, wind speed is observed as time series data, and the current wind speed is related to the past wind speed ...
Rui Fukuoka, Hiroshi Suzuki, Takahiro Kitajima, Akinobu Kuwahara, T. Yasuno   +4 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Wind speed prediction using a hybrid model of EEMD and LSTM considering seasonal features

Energy Reports, 2022
As a clean and renewable energy source, wind power is of great significance for addressing global energy shortages and environmental pollution. However, the uncertainty of wind speed hinders the direct use of wind power, resulting in a high proportion of
Yi Yan, Xuerui Wang, Fei Ren, Zhuliang Shao, Chenlu Tian   +4 more
doaj  

Wind Speed Modeling by Nested ARIMA Processes

Energies, 2018
Wind speed modelling is of increasing interest, both for basic research and for applications, as, e.g., for wind turbine development and strategies to construct large wind power plants. Generally, such modelling is hampered by the non-stationary features
Sokhom Sim, P. Maass, P. Lind
semanticscholar   +1 more source